Repro 2 Flashcards
Do dogs and cats have seminal vesicles?
NO!
T/F: The size of the testes is generally not related to the size of the animal
True
Types of testicular cells
- somatic cells
- germ cells
Interstitium (Inter-tubular) cells
- Leydig cells
- mast cells
- CT
- blood and lymph vessels
Seminiferous tubule (intra-tubular) cells
- peritubular cells
- Sertoli cells
- germ cells
The Leydig cell is the site of _________ in the testis
androgen biosynthesis
These cells are also called supporting cells or the nurse cells
Sertoli cells
Sertoli cells have a ____ population in the seminiferous tubules - they stop dividing in early neonatal peroid
fixed
Tight junctions or the zonula occludens between adjacent Sertoli cells constitute the __________
blood-testis barrier
The blood-testis barrier divides the seminiferous epithelium into ______ and ________ compartments
basal and adluminal
The basal compartment has germ cells in ____
mitosis
The adluminal compartment has germ cells in ______
meiosis
During mitosis and meiosis in the testis, the dividing cells are connected by cytoplasmic bridges. Why?
Allows cells in the same cohort to communicate w/ each other and maintain synchrony of differentiation
What is spermiation?
process by which mature spermatids are released from Sertoli cells into the seminiferous tubule lumen prior to their passage to the epididymis
Residual bodies released from the sperm are phagocytosed by ___________
Sertoli cells
The sperm head consists of ….
nucleus and acrosome
The sperm tail consists of ….
- connecting piece or neck
- middle piece
- principle piece
- end piece
What is the arrangement of microtubules inside the tail of the sperm?
9 + 2 arrangement
9 doublets in a ring with one doublet in the center
T/F: Type A1 cells in the testis can revert to Type A0.
True
It reverts back to a stem cell for sperm production
What is spermatogenesis?
process in which spermatozoa are produced from male primordial germ cells by way of mitosis and meiosis
T/F: Waves of spermatogenesis is a concept in SPACE and the seminiferous epithelial cycle is a concept of TIME.
TRUE!
Note: this is often a T/F question on the test!!!!!!!!
T/F: The duration of spermatogenesis can not be altered by hormonal treatment, changes in temperature, etc.
True
T/F: The duration of spermatogenesis can be easily calculated
true
How is the duration of spermatogenesis calculated?
number of SE cycles x duration of one SE cycle
SE cycle = seminiferous epithelial cycle
What is the importance of cytoplasmic bridges present between developing male germ cells?
To maintain synchrony of differentiation
Factors regulating daily sperm production (4)
- spermatogonial divisions
- seasonal variations (environment)
- cellular degeneration
- hormones
_____________ determine the quantitative yield of sperm.
Spermatogonial divisions
Mitotic divisions controlled by ___________
germ cell/ Sertoli cell ratio
___________ can support only a fixed no. of germ cells
Sertoli cells
“ceiling effect” for sperm output
In summer months, male animals can experience ______ sperm output and sperm motility
decreased
One A1 spermatogonia can result in _____ sperm
512
Optimal thermal environment for normal spermatogenesis is _______, which is approx. 5 degrees C below body temperature
32 degrees C
Scrotum (5)
- relatively thin skin
- sweat glands and sebaceous glands
- lack of subcutaneous layer of fat in the scrotal fascia
- fibromuscular layer in the skin = Tunica Dartos
- intracapsular position of large testicular blood vessels
Regulation of testicular temperature is accomplished by…
scrotum and pampiniform plexus
What fibromuscular lauer in the skin of the scrotum is sensitive to temperature changes?
tunica dartos
Describe the pampiniform plexus in the spermatic cord
The outer membrane of the testicular artery merges with the outer membrane of the testicular vein.
Inflowing arterial blood exchanges heat with outflowing venous blood.
Androgens (4)
- support spematogenesis (maintaienance)
- induce and maintain differentiation of male internal and external reproductive organs
- induce secondary male sex characteristics
- influence sexual behavior
In addition to functions, what do androgens promote? (3)
- protein anabolism
- somatic growth
- regulate secretion of gonadotropins
Functions of FSH in males
- synthesis of ABP, inhibin, activin, and aromatase
- increases LH receptors on Leydig cells
_____ in males leads to the synthesis and secretion of testosterone
LH
___ acts via Sertoli cells to stimulate spermatogenesis (initiation)
FSH
_____ increases the number of spematogonia and spermatocytes
FSH
________ regulates meiosis till pachytene stage
FSH
___ regulates Leydig cell numbers through androgen receptors in interstitial cells
FSH
_____ is necessary for the initiation of spermatogenesis, while _____ is necessary for the maintainance of spermatogenesis.
FSH; Testosterone
______ and __________ reduce FSH secretion
Inhibin and follistatin
_________ increases FSH secretion
Activin
Epithelium of the epididymis?
pseudostratified