Replication Flashcards
What is the process of making an identical copy of DNA called?
Replication
Which enzyme unwinds the DNA double helix during replication?
Helicase
What is the function of DNA polymerase during replication?
Synthesizes new DNA strands
In which direction does DNA replication occur?
5’ to 3’
What is the role of primase in DNA replication?
Synthesizes RNA primers
What is the function of DNA ligase in DNA replication?
Joins Okazaki fragments
What is the role of single-strand binding proteins in DNA replication?
Prevents reannealing of DNA strands
What is the name of the DNA replication process where both strands are synthesized simultaneously?
Semi-conservative replication
Which enzyme proofreads newly synthesized DNA strands during replication?
DNA polymerase III
What is the function of topoisomerase during DNA replication?
Relieves strain in the DNA ahead of the replication fork
What is the term for the short DNA fragments formed on the lagging strand during replication?
Okazaki fragments
Which enzyme removes RNA primers and replaces them with DNA nucleotides during replication?
DNA polymerase I
What is the function of the sliding clamp during DNA replication?
Keeps DNA polymerase attached to the template strand
What is the name of the site where DNA replication begins?
Origin of replication
What is the role of the replisome in DNA replication?
Complex of enzymes involved in replication