Renin Inhibitors

Question 1

Renin Inhibitor Drugs

Answer 1

Aliskiren

“Ali Skiren likes to block renin”

Question 2

Indication for Renin Inhibitors

Answer 2

Hypertension

Question 3

Adverse effects of Renin Inhibitors

Answer 3

Hyperkalemia d/t decrease in Na & H2O

Question 4

Contraindications for Renin Inhibitors

Answer 4

Pregnancy

Question 5

Drug interactions with Renin Inhibitors

Answer 5

FUROSEMIDE: renin inhibitors decrease its diuretic effect

Other RAAS drugs: ACEIs and ARBs

Question 6

Nurse Considerations for Renin-Angiotensin-Aldosterone System (RAAS)

Answer 6

Assess for kidney impairment, Na/H2O depletion, & heart failure.
Assess renal fx & electrolyte labs & obtain pregnancy test.
Dx: Impaired skin integrity r/t to rash, Ineffective tissue perfusion r/t cardiac output changes, & acute pain r/t GI effects & rash
Monitor pt for any situation that may lead to fluid depletion (e.g dehydration, diarrhea, & vomiting)
Educate pt to notify provider when pregnant