Angiotensin II Receptor Blockers (ARBs)

Question 1

Angiotensin II Receptor Blocker Drugs

Answer 1

End in -SARTAN

Candesartan, Irbesartan, Losartan, Olmesartan, Telmisartan, Valsartan

Question 2

Angiotensin II Receptor Blockers Action

Answer 2

Blocks angiotensin II from binding on the receptors of the vascular smooth muscle & in the adrenal cortex.
Prevents vasoconstriction & the release of aldosterone

Question 3

Indications for ARBs (Angiotensin II Receptor Blockers)

Answer 3

Congestive Heart Failure
Hypertension
Diabetic Nephropathy Prevention

Question 4

ARBs Adverse Effects (Hs, GI, R, CNS)

Answer 4

Temporary loss of consciousness r/t to hypotension (syncope), headache, dizziness, & weakness
N/V, abdominal pain
Skin rash
Hyperkalemia
Renal damage r/t inadequate blood flow to the renal artery

Question 5

Contraindications for ARBs (PA)

Answer 5

Pregnancy- BLACK BOX WARNING

Allergy

Question 6

Caution with ARBs

Answer 6

Liver/kidney dysfunction

Hypovolemia

Question 7

Drug Interactions for ARBs

Answer 7

NSAIDs & other RAAS drugs

Question 8

Nurse Considerations

Answer 8

Assess liver impairments & liver fx labs
Administer with or w/out food
Administer with food if pt has GI effects