RAAS: ACE Inhibitors

Question 1

ACE Inhibitors

Answer 1

Angiotensin Converting Enzyme Inhibitors: Block ACE from converting from angiotensin I to angiotensin II. Causes vasodilation, Na & H2O excretion, & small K+ increases in serum

Question 2

ACE Inhibitor Drugs

Answer 2

End in -PRIL

Benazepril, Captopril, Enalapril, Lisinopril, & Ramipril (BENAZE CAPTO a ENALA, LISINO & RAMI)

Question 3

Indications for ACE Inhibitors

CHLD

Answer 3

Congestive Heart Failure
Hypertension
Left Ventricle Dysfunction
Diabetic Nephropathy Prevention

Question 4

ACE Inhibitors Adverse Effects

EHRR

Answer 4

Erectile Dysfunction
Hypotension: dizziness & fatigue
Reflex tachycardia
Renal insufficiency d/t inadequate renal blood flow

Question 5

Ace Inhibitors Contraindications

AIP

Answer 5

Allergy
Impaired Renal Fx
Pregnancy

Question 6

Drug Interactions Ace Inhibitors

Answer 6

Allopurinol (used for gout): increase risk of hypersensitivity reaction
NSAIDs: Decrease the effects of ACE inhibitors
Other drugs affects the RAAS

Question 7

Other Adverse Effects ACE Inhibitors (HDPRN)

Answer 7

Pancytopenia: Low RBCs, WBCs, and platelets d/t bone marrow depression
N/V, abdominal pain
Rash
Hyperkalemia
Dry cough

Question 8

Nursing Considerations

Answer 8

Assess CBC labs for pancytopenia
Administer on empty stomach 1 hr prior or 2 hr after meals
Educate pt on cough that it may persist for 1 month after discontinuation
Educate pt to NOT STOP MEDICATIONS ABRUPTLY d/t rebound hypertension

Question 9

Benefits of using ACE Inhibitors

Answer 9

Protective agents for diabetics as it protects the renal artery.
They can be used with Digoxin or Diuretics in heart failure to prevent & reverse heart enlargement & decreases cardiac overload.