renal transplant Flashcards
what is a chronic kidney disease
long term condition where kidneys can no longer filter waste and excess fluids
stages
- normal function -signs of kindey damage
2.midly decreased kidney function (60-89
3.moderate decreased kidney function (30-59 - severe damage (15-29
5.kidney failure ( less than 15
symtoms of kidney failure
fatigue, itch, urine output, fluid overload, vomiting, anorexia, nausea
causes
-diabetes
-HBP
-Glomerulonephritis
-polycystic kidney disease
-heart disease/obesity
how to fix this
prevent not cure
-meds-control hbp, blood sugar, cholestrol
-dietry changes- reduce salt, protein, and potassium intake
-dialysis
-transplant- not a lot to be done
control syptoms
negative QoL
what is a acute kidney injury
sudden decline in either days or hours
and is usually reversible
what causes AKIs
prerenal-reduced blood flow
intrintic-direct damage to kindeys-infection
postrenal - obstruction of urine flow
symptoms
-decreased urine output
-swelling
-fever
-back pain
-fatigue
what can be done?
- address underlying issue e.g imrpoving blood flow
- stopping nephrotoric medications
- draining obsturction
- temprorary dialysis \
positives of transplants
-patient returns to normal QoL
-normla life expecatany
negatives of transplant
-potential surgical complications
-fialure to work
-psot op thrombosis
-wound deniscience
-risk of infection-immunosuppression
-weakining of the immune system- bacterial, UTI, pneumonia
types of kidney transplants
-DCD
-DBD
-paired exchange
-alteristic
incomatible transplants
HLA- Human leukocyte antigen
-proteins on cell surface that identify self cells
-markers do not match
-increase chance of rejection
ABO- blood group incompatibility
ABO antibodies attack donor kidney’ blood vessles
-increaase chsnce of rejection
sources
Nationial kidney foundation
national institute of diabetes, digestive and kidney diseases
bloom and reese, 2007
expansion on causes:diabetes
diabetic nephropathy:
-high blood sugar damages blood vessels
-longterm damages nephrons
-causes kidneys to work harder=fibrosis
hypertension
damages all blood vessles and kidney ones
reduces ability to filter waste products
glomerulonephritis
inflammation of glomeruli (filters)
inflammation can lead to infection and autoimmunity
polycystic kidney disease
genetic disroder were cyts develop innthe kidneys
damamges surrounding kindey tissues
heart disease/obesity
related to hypertension and diabetes
poor circulation= kidney ischeamia