Renal System Flashcards
What are five abnormal findings in urine
- Glucose
- Hematuria
- Proteinuria
- Bacteriuria
- WBC
What gives urine the color?
Urobilinogen
byproduct of bilirubin
Dark urine can be an indicator of?
Hepatic (liver) failure or rhabdomyolysis
Define
glomerulonephritis
What would it cause?
inflammation of the tiny filters in the kidneys (glomeruli) leading to increased permeability of abnormal constituents.
What 3 conditions can cause AKI pre-renal?
- Hypovolemia
- Hypotension
- Obstruction or vasoconstriction
What can causes issues post-renal (bladder/urethra)
Obstruction (e.g., kidney stones, inflammation of those structures)
What are 3 commonly used nephrotoxic agents?
- Contrast dyes
- Antibiotics
- NSAIDS
acetaminophen-induced nephrotoxicity is rare, more likely to dmg liver.
What are signs of renal (kidney) compromise?
- Decreased urine output
- Elevated Renal labs (BUN and Creatinine)
What is the treatment for AKI?
Acute Kidney Injury
Treat underlying cause (may use temporary dialysis, take away antibiotics)
What are the 4 causes of anemia in CKD?
Chronic Kidney Disease (CKD)
- Loss of ability to activate vitamin D.
- Loss of ability to produce erythropoietin
- Blood loss through damaged glomerulus
- Increased fluid retention dilutes the blood
What are the 3 causes of CKD?
Chronic Kidney Disease (CKD)
- Diabetes mellitus
- Hypertension
- AKI
2/3 of all cases of CKD is associated w/ DM and HTN.
What causes itching in CKD?
Chronic Kidney Disease
Uremic frost (build of up urea)
Why would patients w/ CKD experience difficulty concentrating?
Patients may state “fogginess or trouble remembering”
Build up of waste products in the blood (e.g., increase ammonia, uric acid)
What are 2 causes of fatigue in patients w/ CKD?
- Main reason is anemia.
- Secondary, low BP during dialysis
What causes HTN in patients w/ CKD?
CKD patients hold onto fluid increasing workload on heart.
What are the directions for completing a 24 hour urine test?
Discard the first urine output; then start the 24 hour clock. All subsequent urine is stored in refridgerator.
- What is the expected GFR in clinical settings?
- What is the normal GFR in laboratory setting?
- eGFR > 60 ml/min
- GFR = 125 ml/min
What are two types of dialysis systems?
Hemodialysis and peritoneal dialysis
What should fistulas be assessed for?
- Thrills (vibratory movement through stethoscope)
- Bruit (ascultation should heart turbulent blood flow)
what should be avoided with fistulas?
- IV sticks on fistula
- Assessing BP on that area
What are the 3 signs of peritonitis?
- Pain, firmness in abdomen area
- Cloudy dialysate
- Signs of infection (fever, WBC, malaise)
What intervention is recommended for patients of peritoneal dialysis that is experiencing SOB or difficulty emptying dialysate?
Repositioning
Where is the cather inserted for hemodialysis?
Superior vena cava
What is a fistula?
the fusion of a vein and artery as a permanant solution to dialysis through cath
makes vessel able to handle large blood flow from dialysis
What 4 things should be conisidered before a patient undergoes hemodialysis?
- Low BP (give vasopressors if low)
- Temperature
- Low electrolytes
- Hold antibiotics/medications that decrease BP
Monitor nutrition and fluid levels
What 4 medications are commonly prescribed to dialysis patients?
- Synthetic EPO (darbepoetin alfa)
- Iron (ferrous sulfate)
- Electrolyte supplement (especially potassium)
- BP medication can go either way
What is sodium polystyrene (Kayexalate) used for?
Treats hyperkalemia
(exchanges sodium with potassium ions from the intestinal cells)
Decreases K+ levels
What is the relationship b/w phosphorus and calcium?
Phosphorus in plasma takes calcium from bone and put it into plasma.
Risk of brittle bones
What foods should be avoided to decrease phosphorus?
- Processed food (fast food, deli meats, pizza)
- Dark cola, beer
- Deli meats
- Diary
P W/ 3 Ds
What would be the expected GFR for ESRD patient?
GFR < 15 ml/min
How is GFR collected in laboratory setting vs clinical setting?
- Laboratory through 24-hr urine test
- Clinical through blood test (eGFR)
What are the two normal UO measures?
- 1mL/kg/hr
- > 30 mL/hr*
*used when weight of patient is unknown