renal structure and function Flashcards
What colour and shape are the kidneys?
It is a reddish colour and a bean shape
- How much does each kidney weigh?
134 grams
Where does each kidney lie?
They are lying on either side of the vertebral column between the levels of the 12th thoracic and third lumbar vertebrae (T12 and L3)
What does lack of blood supply lead to in the kidney?
kidney shrinkage
Between what levels are the kidneys found?
T12 and L3
Outside which membrane are the kidneys found?
outside the peritoneum
- Which kidney is slightly inferior (lower) and why?
right kidney to accommodate for the Liver.
- What two types of pole are found in each kidney?
superiorandinferior pole
- What shape is the lateral surface of the kidney?
convex
- What shape is the medial surface of the kidney?
concave
- What is the vertical cleft of the kidney called?
the renal hilus
- Where does the renal hinus lead to?
the renal sinus
- What gland can be located on top of the kidney?
suprarenal glandor theadrenal gland
- What is the general main function of the kidneys ?
To filter the blood
- What is are the 4 homeostatic functions of the kidney?
- Maintains body water balance
- Regulates quantity & concentration of ECF ions
- Maintains plasma volume & osmolarity
- Assists in acid-base balance
- What are the excretory functions of the kidneys?
- Excretes end-products of body metabolism
- Urea (protein), creatinine (muscle), uric acid (DNA & RNA), bilirubin (haemoglobin)
- Excretes foreign compounds
- What are the secretory functions of the kidneys?
- Produces & secretes erythropoietin
- Secretes renin, kalikrein, prostaglandins
- Converts vitamin D into its active form (1,25 dihydroxycholecalciferol (D3)
- What percentage of cardiac circulation do both kidneys receive?
25%
- How are both renal arteries positioned relative to the renal veins
posteriorly
- Which renal vein is longer and why
the left because it goes over the aorta
- Which renal artery is longer and why
right because it goes under the inferior vena cava
- Outline the order of the types of vessels starting with the aorta and ending with the glomerulus
- aorta
- renal artery
- segmental artery
- interlobar artery
- afferent arteriole
- Glomerulus
Outline the order of the types of vessels starting with the Glomerulus and ending with the inferior vena cava
- efferent arteriole
- Peritubular capillaries and vasa recta
- Interlobular vein
- Renal vein
- inferior vena cava
- What percentage of nephrons in the kidney are juxtamedullary
20%
what percentage of the nephrons in the kidney are cortical?
80%
- What is the function of the juxtamedullary nephron
Concentrating urine
- What are 2 features of the juxtamedullary nephron
- Thin/thick ascending limbs of Loop of Henle
- §Vasa recta (hair-pin loop capillaries)
- What is the function of the cortical nephron
Filtration
- What is a feature of the cortical nephron
has peritubular capillaries
- Outline the basic structure of the nephron starting with afferent arteriole and ending with urine into ureter
- Afferent arteriole,
- bowman’s capsule/ efferent artiole,
- proximal convoluted tubule,
- loop of henle,
- distal convoluted tubule,
- collecting duct,
- duct of benini
- urine to ureter
- What is the condition called when you have no blood travelling to the kidneys
Renal Artery stenosis
- What is the origin of the interlobular artery
segmented artery
- What is the arteriole that enters the kidney called?
afferent arteriole
- What is the arteriole that exits the kidney called
efferent arteriole
- What is the function of the Proximal convoluted tubule (PCT)?
Most reabsorption of substances like glucose, water, ions and amino acids
- What are the 3 features of the PCT that help it perform its function
Microvilli
Long & thin
Mitochrondia
What is the function of the loop of henle?
to produce concentrated urine by reabsorbing water and sodium chloride
- What are the 2 features of the loop of henle that help it perform its function?
- has thick and thin portions
- descending limb (thin) and Ascending limb (thick) have different permeabilities
what are 3 features of the Distal convoluted tubule?
- hormonally regulated action
- less microvilli
- Low water permeability
what are 3 features of the collecting duct
- intercalated and principal cells
- hormonally regulated action (ADH, Aldosterone, atrial natriuretic peptide