RENAL STONES Flashcards
⚡⚡ MOST COMMON RENAL STONE
⚡⚡ MOST COMMON BLADDER STONE
⚡⚡ MOST COMMON 1° BLADDER STONE
⚡⚡ MOST COMMON PROSTATE STONE
⚡⚡ MOST COMMON RENAL STONE
🎯 Calcium OXALATE Stones
⚡⚡ MOST COMMON BLADDER STONE
🎯 Uric Acid > STRUVITE Stones
⚡⚡ MOST COMMON 1° BLADDER STONE
🎯 Ammonium URATE
⚡⚡ MOST COMMON PROSTATE STONE
🎯 CALCIUM PHOSPHATE STONE
CALCIUM PHOSPHATE STONE is the MOST COMMON STONE in
- Prostate
- Salivary Gland
Stone FORMATION INHIBITING Substances
- Citrate
- Tamm Horsefall Protein
⭐ CONCENTRATION PRODUCT
⭐ SATURATION PRODUCT
⭐ FORMATION PRODUCT
⭐ CONCENTRATION PRODUCT
🎯 Amount of Solute in SOLUTION
⭐ SATURATION PRODUCT
🎯 MAXIMUM AMOUNT OF SOLUTE IN SOLUTION
⭐ FORMATION PRODUCT
🎯 MAXIMUM AMOUNT OF SOLUTE IN SOLUTION ➕ Removing effect of STONE INHIBITING FACTORS
Stone formation occurs when
Concentration product > Formation Product
Radio-opaque Renal Stones
🧠⚡PCO2 ⚡
- Phosphate
- Cysteine
- Oxalate Ca2+
Radio-lucent Renal Stones
🧠⚡Translucent In Ur X-ray! DO! ⚡
- Triamterene
- Indinavir
- Uric acid
- ammonium Urate.
- Xanthine
- Dihydroxyadenine
- Orotic acid
- Drug stones
- Cephalosporin
- Cysteine
- Ephedrine
- Guaifenesin
- Sulphonamides
- Magnesium trisilicate
LARGE SIZED RENAL STONES
- Staghorn / Triple PHOSPHATE stone
- Bladder Stones
MULBERRY STONES
Calcium oxalate stones
DUE TO: SPICULATED MARGINS
Shape of STONES
Calcium Oxalate stones
✨ Monohydrate ➡️ Dumb bell Shaped
✨ Dihydrate ➡️ Envelope shaped
Etiology of KIDNEY STONES
🧠⚡HIDE ⚡
Stones formed in ALKALINE URINE
- Struvite / Triple phosphate stone
- Calcium Phosphate
Stones formed in ACIDIC URINE
🧠💡CCU💡
- Calcium Oxalate
- Cysteine
- Uric Acid Stone
Triple Phosphate Stone
Composition
🧠⚡ CAM-P⚡
Phosphates of
1. Calcium
2. Ammonium
3. Magnesium
💊💉 MANAGEMENT of Calcium OXALATE STONES
- Decrease FAT in Diet
- ⬆️ Ca2+ in DIET
- ⬆️⬆️ Pyridoxine in DIET
- Cholestyramine: Binds to Oxalate in GUT
Why ⬆️ Calcium in diet when in MANAGEMENT of Calcium OXALATE stones?
Calcium will Bind to OXALATE in GUT
⬇️
Less OXALATE ABSORPTION
💊💉 MANAGEMENT of RECURRENT STRUVITE (OR) TRIPLE PHOSPHATE Stones
Acetohydroxamic acid
⬇️
Irreversible ⛔ of Urease enzyme
VERY HARD STONES are:
🧠💡Difficult to break by ESWL💡
🧠💡BHC2💡
- Calcium OXALATE monohydrate
- Cysteine
- Brushite
- Hydroxyapatite
💊💉 MANAGEMENT of RECURRENT CYSTEINE STONE
🧠⚡CD⚡
⭐ Cystine Complexing Agents
D-penicillamine
Alpha-mercaptopropionylglycine (MPG)
Glass shrads like Crystals seen in
Uric acid stones
💊💉 MANAGEMENT of RECURRENT URIC ACID STONES
Allopurinol
Uric acid stones are seen in
- TUMOUR lysis Syndrome
- Gout
Xanthine stones
Brick red
Triamterene stones
Anti-HTN medication leading to RADIOLUCENT Stones
Indinavir stones
Protease inhibitor in AIDS leading to Radiolucent calculi
Ammonium Urate Stones seen in
- IBD
- Laxative Abuse