Renal Regulation Of H

Question 1

In normal circumstances, ________ of the filtered load of HCO3 is reabsorbed

Answer 1

The entire amount

Question 2

The primary urinary buffer is

Answer 2

Phosphate

Question 3

Glutamate is metabolized to NH4 and HCO3- in the ________

Answer 3

Proximal tubule

Question 4

The NH4 that is secreted to the lumen in the proximal tubule is reabsorbed ______

Answer 4

Primarily in the thick ascending limb of Henle’s loop

Question 5

For each molecule of NH4 excreted in the urine, a “new” molecule of ______

Answer 5

HCO3- is added back to the ECF

Question 6

What are the two mechanisms to make “new “ bicarbonate ?

Answer 6

1. Secretion of H ions which combine w/ non bicarbonate buffers supplied by filtration (primary buffer is phosphate)
2. Catabolism of glutamine in assoc w/ excretion of ammonium in the urine.

Question 7

Type of intercalated cell that secretes bicarbonate

Answer 7

Type B intercalated cells

Question 8

Type of intercalated cells that are in the distal convoluted tubule and collecting duct system that reabsorb virtually all remaining filtered bicarb as well as any secreted bicarb

Produces titratable acid

Answer 8

Type A

Question 9

What is ammonium in countertransport with when transported to the lumen ?

Answer 9

Na

Question 10

Positive values of net acid excretion means a _____ of bicarbonate

Answer 10

Loss

Question 11

Negative values for net acid excretion means you have a _____ of bicarbonate

Answer 11

Gain