Body Fluid Compartments Flashcards

1
Q

The percentage of total body water is ________ to age

A

Inversely related

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2
Q

The percentage of total body water is ______ to the degree of body fat

A

Inversely related

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3
Q

Adipose tissue contains ________ amount of water

A

Very litle

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4
Q

The percentage of total body water is _____ in adult females than in adult males due to subcutaneous layer of adipose tissue.

A

Lower

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5
Q

Total body water is distributed among which 3 major compartments

A

Blood plasma

Interstitial fluid

Intracellular fluid

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6
Q

Plasma and interstitial fluid are separated by

A

Capillaries

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7
Q

Intraocular, cerebrospinal, and the fluid in transit in the lumina of epithelial organs is the 4th, smaller fluid compartment that is called the _______ fluid compartment

A

Transcellular

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8
Q

What 4 organs communicate the extracellular fluid with the external environment

A

Ailmentary canal
Lungs
Kidneys
Skin

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9
Q

Major intracellular fluid ion is ?

A

Potassium

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10
Q

Major extracellular fluid ions ?

A

Sodium and chlorid

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11
Q

Protein concentration of plasma is _____ to ISF

A

Greater than in respect to

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12
Q

Ionic concentration fo plasma is ____ to the ionic composition of the ISF

A

Similar to

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13
Q

Substance used in the determination of exctracellular fluid volume

A

Inulin

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14
Q

Substance used in the determination of plasma volume

A

I-albumin 131 (or Evan’s blue dye)

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15
Q

When calculating the volume of extracellular fluid when using inulin, what has to be taken into account?

A

The amount of inulin that is naturally secreted by the kidneys

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16
Q

Substance used to determine the total body water?

A

Antipyrine (or deuterated water or titrate water)

Can rapidly permeate cell membranes. Distributes uniformly throughout the ECF and ICF compartments

17
Q

Complications associated in using tritiated isotope water in calculating total body water?

A

This water is lost through every route possible to lose water from the body

18
Q

Factors that can cause extracellular and intracellular volumes to change

A

Ingestion of water

Dehydration

IV infusion

Large amount of fluid loss from GI tract

Abnormal amount of fluid loss from sweating or kidneys

19
Q

Extracellular fluid becomes hyperosmotic by one of which two way?

A

Water loss

Na Retention

20
Q

ECF becomes hyposmotic by what ?

A

Water gain

Na Loss

21
Q

Common causes of increased ADH secretion

A

Neuropsychiatric disorders

Drugs

Pulmonary disease

Postoperative patient

22
Q

Acute symptoms with [Na] between 120 meq/L and 125 meq/L (plasma)

A

Nausea and malaise

This is hyponatremia

23
Q

Acute symptoms with [Na] (plasma) between 110meq/L and 120 meq/L ?

A

Headache and lethargy

This is hyponatremia

24
Q

Acute symptoms with [Na] (plasma) below 110meq/L

A

Seizures

Coma

Permanent neurologic deficits

Death

(Severe hyponatremia)

25
Q

Are there chronic symptoms with hyposmolarity (hyponatremia)

A

No.

There is brain osmotic adaptation.

26
Q

Explain brain osmotic adaptation

A

Cerebral swelling will increase the flow of brain ISF towards the CSF decreasing the amount of swelling

Solutes move out of brain cells decreasing the amount of brain cell swelling

27
Q

Number of solute particles per 1L of water

A

Osmolarity

28
Q

Number of solute particles in 1kg of water

A

Osmolality

29
Q

Functional unit of the kidney is the

A

Nephron

30
Q

Renal disease with bilateral inflammatory changes in the glomeruli

Characterized by blood in urine

Protein in urine

Decreased urinary output

Edema

A

Glomerulonephritis