RENAL PHYSIOLOGY/URINALYSIS Flashcards
The most important function of the kidney is its
ability to maintain the stability of the ECF volume, electrolyte composition and osmolarity
What is the 60-40-15-5 Rule?
60% = water
40% = intracellular fluid
20% = extracellular fluid
–> 15% = interstitial fluid
–> 5% = plasma
Where is the kidney located?
T12-L3
Where is the kidney situated?
retroperitoneum
The kidney is divided into:
- Outer: Renal Cortex
- Inner: Renal Medulla
Fill in the blanks: Formed ____________ the kidney, ____________ the ureter, and is_________________________.
urine exits, through, renal pelvis, stored in the urinary bladder
Functions:
- H2O balance
- osmolarity
- electrolytes
- plasma volume
- Acid-Base
- Eliminating waste products
- Eliminating drugs
- Erythropoietin
- blood pressure through renin production
- Vitamin D to its active form
What is the unit of the kidney?
Nephron
What is the nephron?
structural and functional units
What is nephron made up of?
- vascular component
- tubular component
- combined component
Two major types of Nephrons
- Cortical Nephron
- Juxtamedullary Nephron
Make up 75% of nephrons
Cortical Nephron
Make up 25% of nephrons
Juxtamedullary Nephron
Located in the renal cortex
Cortical Nephron
Located in the corticomedullary junction
Juxtamedullary Nephron
Shorter Loops of Henle
Cortical Nephron
Longer Loops of Henle
Juxtamedullary Nephron
Has peritubular capillaries
Cortical Nephron
Has vasa recta
Juxtamedullary Nephron
Vascular Component consists of
- Afferent arteriole
- Glomerulus
- Efferent arteriole
- Peritubular arteriole
- Vasa Recta
carries blood to the glomerulus
Afferent arteriole
tuft of capillaries that filters plasma into the tubular component
Glomerulus
carries blood away from the glomerulus
Efferent arteriole
involved in the exchange of substances with the fluid in the tubular component
Peritubular capillaries
serves as an osmotic exchanger for the concentration of urine
Vasa recta
Tubular Component consists of
- Bowman’s Capsule
- Proximal Tubule
- Loop of Henle
- Distal Tubule
- Collecting Duct
collects the glomerular filtrate
Bowman’s capsule
Site of reabsorption of 100% of Glucose and amino acids
Proximal Tubule
Establishes the osmolarity of urine
Loop of Henle
Descending limb: permeable to
water