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Physiology > Renal Physiology > Flashcards

Renal Physiology Flashcards

1
Q

Nephron

A

Smallest structural functionl unit of kidney

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2
Q

Cortical nephrons

A

80% entirally in cortext filters blood

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3
Q

Juxtamedullary nephrons

A

Shifted towards medulla concentrate medulla with solute

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4
Q

Renal vasculature

A

Afferent arteriole, glamerous to filter (fenistrated caps), efferent arterirol, peritubular caps or vasa recta

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5
Q

Efferent ateriole with peritubular caps

A

Wrap around nephron to reabsorb good stuff

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6
Q

Reabsorption

A

Fluid into blood vessel

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7
Q

Secretion

A

From blood vessel

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8
Q

Glomerulus

A

Hydrostatic pressure drives water and solutes across glomerular filtration membrane and into bowmans space

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9
Q

Proximal convoluted tubule

A

Reabsorb good stuff 100% efficient

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10
Q

Descending limb

A

Reabsorb water

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11
Q

Ascending limb

A

Salt symporters for salt reabsorbtion into medulla

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12
Q

Distal convoluted tubual

A

Secretion

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13
Q

Collecting duct

A

Reabsorb water if ADH is present. ADH puts aquporins in CD to create a pathway for water to leave

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14
Q

Glomerular filtration mebrane

A

Podicytes are finger like projections to enhance filtration form pedicels to wrap around blood vessels

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15
Q

Glomerular filtration pressure

A

16 mmHg forcing fluid into PCT (glomerular hydrostatic pressure+cap osmotic pressure)-(glomerular osmotic pressure+cap hydroststic pressure)

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16
Q

Hemodialysis

A

Artificial kidney that takes blood frim artery passes it through dialysis solution tk filter blood and back into veins

17
Q

PCT reabsorbs sodium and water by

A

Primary active transport of sodium and urea and water and secondary active transport by SGLTs that bring in glucose, amino acids, and vitamins

18
Q

Caffine and theophylline work on PCT

A

By causing diuresis by enhancing sodium and water excretion

19
Q

Loop of henle

A

Has Na/K pump bringing K in to use NKCC2 to bring in K Cl and Na and K/Cl symportor to leave K and CL leaving Na and Cl in ECF causing salt

20
Q

Loop diuretics

A

Inhibit NKCC2 in TAL so there is no gradiant and salt stays in urine. For edema and high blood pressure

21
Q

Use DCT to lower blood pressure

A

Give thiazides to inhibit Na/Cl symportor

22
Q

Renin andiotensis aldosterone system (RAAS)

A

Low blood pressure understreches afferent arteriole which causes JG cells to produce renin which converts angiotensinogen into agiotensin I and ACE convets into II to constrict arterioles, increase aldosterone secretion, increase thirst, increase ADH, increase sympa

23
Q

Angiotensinogen

A

A zymogen that is always circulating

24
Q

ACE inhibitors and angiotensin II receptor blockers

A

Treat hypertenion and lowe blood pressure

Physiology (6 decks)

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