Cardiovascular System Flashcards
End diastolic volume
Amount of blood left in the heart at the end of relaxation. 120ml
End systolic volume
Amount of blood left in the heart after contraction. 50ml
Stroke volume
Amount pumped out per beat. EDV-ESV. 70ml
Heart failure
Chronic hypertenion
Hypertrophic cardiomyopathy
When a person has hypertension resistance to flow is higher and the heart has to contract harder. The muscle grows and then the sarcomeres dont line up and the heart gets stiffer and contracts weaker. This causes less blood to be pumped out
Mitral valve prolaspe
Hernation or bulging of the AV valve into the left atrium
Atrial regurgitation
The seal of the left AV valve is compromised and blood can leak back into the atrium
Heart murmur
The hissing sound of blood leaking back into the atrium
Lubb noise
First heart sound. AV valve closing
Dupp
Second heart sound. Semi lunar valves close
If lusitropy (heart rate) is lower what happens to stroke volume?
It is greater
Ejection Fraction
Efficiency of the pump. SV/EDV.
Normal ejection fraction
Greater than or equal to 55%
Cardiac output equals
SV x HR
Heart rate is generated by
The SA node
Sympathetic does what to heart rate
Increases
Parasympathetic does what to heart rate?
Decreases
Upper limit for conduction through AV node
250 bpm
Heart rate 160-180 decrease CO because
The heart is beating so fast that it doesnt have time to relax fully which means not enough blood back to heart to pump back out
Why is there a delay through the AV node
So the atrium and ventricals dont contract at the same time
Ways to control SV
Increase sympathetic stimulation, increase intracellular calcium and increase contractility
Frank-Starling Law
The heart can intrinsically adjust its SV in response to changes in venous return
Preload
Blood returning to the heart
Ways to increase SV
Increase contractility and increase EDV
Afterload
The pressure blood has to pump against; blood pumping against blood
Increase preload will do what?
Increase EDV to increase SV
Increase afterload will do what?
Increase EDV to decrese SV
Increase inotropy (contractility) will do what?
Decrease ESV to increase SV
Systolic pressure
Blood in CVS during contraction. The left ventrical is pushing out
Diastolic pressure
Blood in CVS during relax. Left ventrical relaxing