Renal Physiology Flashcards

1
Q

What is the net filtration pressure on the arterial side of a capillary?

A

10 mmHg

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2
Q

What is the net filtration pressure on the venous side of a capillary?

A
  • 8 mmHg
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3
Q

Hypernatremia

A

Increased Na concentration

Water loss, Na excess

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4
Q

Hyponatremia

A

Decreased Na concentration

Water excess, Na loss

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5
Q

Normal plasma Na concentration?

A

140 - 145 mmol/L

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6
Q

The brain cannot increase its volume by more than ___% without herniation.

A

10%

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7
Q

What happens to cells in hypotonic solution?

A

Cells swell

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8
Q

What happens to cells in hypertonic solution?

A

Cells shrink

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9
Q

Fluid percentages in each compartment.

A

Plasma: 3L
Interstitial fluid: 11 L
Intracellular fluid: 28 L

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10
Q

How many liters of water do the kidneys filter each day?

A

Filters 180.
Reabsorb 179
Secretes 1

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11
Q

Normal GFR

A

125 ml/min

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12
Q

Whats the net filtration pressure in the glomerulus?

A

10 mmHg

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13
Q

What do the afferent and efferent arterioles do in a hypertensive state?

A

The afferent constricts

The efferent dilates

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14
Q

How much cardiac output reaches the kidneys?

A

22%

Whoa

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15
Q

What will the afferent arteriole do in response to decreased GFR

A

Dilate

Increase GFR

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16
Q

Where do the kidneys sit relative to vertebrae?

A

T12 to L2

17
Q

What cells is the PCT made of?

A

Epithelial cells with long microvilli

18
Q

PCT absorbs about __% of filtrate.

A

65%

19
Q

How many glomeruli does each kidney have?

A

1,000,000

20
Q

Transport maximum

A

Some substances (glucose, amino acids, phosphate) have a maximum that can be absorbed. So if filtration exceeds reabsorption maximum … they will be excreted in the urine.

21
Q

Can the thin descending loop of henle reabsorb water?

A

Yes.

22
Q

Is the thick ascending loop permeable to water?

A

No.

23
Q

Which part of the kidneys are the glomeruli in?

A

Cortex

24
Q

What makes the DCT special?

A

It is subject to hormonal control

Aldosterone.

25
Q

Which type of nephron sets the concentration gradient?

A

Juxtaglomerular

only 30% of nephrons

26
Q

Atrial natriuretic factor

A

Released by atrial myocardium in response to HTN
Inhibits sodium and water reabs.
Decreases BP

27
Q

Which hormone acts on the collecting ducts?

A

ADH

28
Q

What is glucose cotransported with?

A

Sodium

29
Q

What is glucose cotransported with?

A

Sodium

30
Q

Whats the osmolarity in the cortex?

A

300