Renal Infective disorders: UTI, Pyelonephritis, and stones Flashcards
1
Q
UTI etiology
A
- Leading cause of systemic infections in older adults
- Women are more vulnerable
- Seperated into upper and lower GU tract
- Most common cause is E-coli (Stool)
- Occurs mainly in sexually active women (Diaphram, pregnancy) and post menopausal women
- Cath placement, straight or indwelling
- DM
- Older adults (Decreased bladder tone)
- Neurogenic disorders (Stroke, neuro bladder)
- Gout
- Instrumentation
2
Q
Upper UTI
A
- Kidneys and ureters
- Pyelonephritis
3
Q
Lower UTI
A
- Bladder and urethra
- Cystitis
4
Q
Diagnosis and S+S UTI
A
- Done on a history and S+S
-
Labs: Urinalysis (Clean catch/sterile)
- 100,000 organisms/ml of urine or less with S+S
- CT and kidney scans, obstruction, abscess, tumors, cyst
-
S+S: Dysuria, urinary frequency or urgency, cloudy foul odor, hematuria, lower back pain
- Urosepsis: Shock
5
Q
Medical mgmt of UTI
A
- Lower UTI: Short course antibiotic
- Upper UTI: Longer antimicrobial therapy
- Pain relief
- Antispasmodic agents (Bladder irritability and pain (Ditropan))
- Urinary anesthetic (Pyridium, (Phenazopyridine HCL), (AZO))
finish entire course of antibiotics even if they are feeling better
6
Q
UTI prevention
A
- Adequate hydration (Fluids and cranberry juice)
- Perineal care
- Afterintercourse care
- Showers over baths
- Cotton underwear, avoid tight and restrictive
7
Q
What bevs increase risk of UTI
A
- Coffee
- Tea
- Alc
- Citrus
- Cola
8
Q
CAUTI prevention
A
- Aseptic technique and hygiene
- Keep cath bag below the level of bladder to enable flow
- Cath care (Keep clean)
- Hydration unless contraindicated
- Early ambulation
- Assess volume and characteristics of urine, S+S of infection
- EBP guidelines on early cath removal
9
Q
Acute Pyelonephritis
A
- Upper GU infection, bacterial infection of renal pelvis, tubules and interstitial tissue of one or both kidneys
- Can become chronic
10
Q
Causes of Acute Pyelonephritis
A
- Upwards spread of bacteria from the bladder
- Systemic sources from blood stream (TB infection)
- Urinary retention
- Urinary obstruction (Bladder or prostate tumors, strictures, benign prostatic hyperplasia, urinary stones)
- May progress to a chronic condition
11
Q
Acute Pyelonephritis: Diagnostics
A
- Urinalysis with culture and screen
- Ultrasound
- CT
- IV pyelogram
12
Q
Acute Pyelonephritis: Clinical manifestations
A
- Chills
- Fever
- Leukocytosis
- Bacteriuria
- Pyuria
- Low back pain/ flank pain
- N+V
- Headache/ malaise
- Painful urination
- Pain and tenderness in CVA
- Urinary urgency and frequency
13
Q
Acute Pyelonephritis: mgmt
A
- Outpatient: 2 wk antibiotic therapy
- Make sure they take the entire course of antibiotics
- Hospital mgmt: S+S of sepsis, dehydration N+V
- May need 6 wk antibiotic therapy with relapses (Repeat urine cultures after completion of antibiotics)
- Adequate hydration (Oral or IV)
14
Q
Urolithiasis
A
- Stones (calculi) in the urinary tract
15
Q
Nephrolithiasis
A
Stones (Calculi) in the kidney
16
Q
Incidence of Renal Calculi
A
Starts ages 30-50
2x rate in men
17
Q
Patho Renal Calculi
A
- Stone formation from supersaturation of calcium oxalate/phosphate and uric acid
- Can occur anywhere from kidney to bladder
- Vary in size: From granular to orange size
- Predisposing factors:
- Dehydration, infection, stasis, immobility
- Hypercalcemia
18
Q
Renal Calculi: Calcium stones
A
- 75% of all stones
- Calcium oxalate/phosphate
- Oxalate: Naturally occuring substance occurring in rhubarb, spinach, beets, nuts, chocolate (eating these can increase levels putting you at risk)
- Liver produces oxalate
19
Q
Risk factors for calcium stones
A
- Hyperparathyroidism (Increases serum Ca)
- Cancers (Leukemia, multiple myeloma)
- Dehydration
- Granulomatous diseases (Sarcoidosis, TB), Increases vitamin D production of granulomatous tissue
- Excessive intake of vitamin D and milk
- Myeloproliferative diseases (Polycythemia vera)
20
Q
Renal Calculi: Struvite stones
A
- 15% of incidence, occurring from an infection (UTI)
- Can grow quickly, becoming large with few S+S with little warning
- Form in persistently Alkaline, ammonia rich urine presence of urease splitting bacteria (Pseudo, klebsiella, staph, mycoplasma)
- Predisposing factors neurogenic bladder, and recurrent UTI