Renal Dysfunction Flashcards
1
Q
What is Glomerulonephritis (GN)?
A
Immune-mediated damage to filtration membrane
2
Q
What is the difference between primary and secondary Glomerulonephritis?
A
Primary
- Post-strptococcal or other infections
Secondary
- Following SLE, diabetes mellitus, amyloidosis hypertension
3
Q
What does Glomerulonephritis cause?
A
- Inflammation of the glomerulus
- Inflamed glomerulus is less efficient causing a decrease in Glomerular Filtration Rate (GFR)
- Inflammation causes filtration membrane to become ‘leaky’ (blood cells and large proteins)
4
Q
What is the cause for Glomerulonephritis?
A
Type III hypersensitivity reaction
5
Q
What is the difference between Nephritic and Nephrotic Syndrome?
A
Nephritic Syndrome is the inflammation of the glomerulus
Nephrotic Syndrome is where there is ongoing leaky basement membrane often leading to protein in urine
6
Q
What is Renal Failure?
A
Where their is an impaired glomerular filtration rate with it being 40% less than normal
