renal and urologic structure Flashcards

1
Q

upper urinary system

A

kidneys (form urine)
ureters (drains urine)

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2
Q

lower urinary system

A

bladder (stores urine)
urethra (outflow of urine)

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3
Q

kidneys

A

adrenal gland on top of each
hilus on medial side

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4
Q

nephron

A

cortex and medulla (loop of Henle and collecting tubules)
main functional unit of the kidneys

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5
Q

nephron function

A

tubular reabsorption, secretion, transport, and excretion
primary function = filtration

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6
Q

ADH

A

secreted by the posterior pituitary
increase water permeability + reabsorption
decrease urine output

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7
Q

Aldosterone

A

adrenal cortex
epithelia cells int he distal tubule + collecting duct to reabsorb sodium + excrete potassium

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8
Q

Kidney function: regulate volume + make of ECF

A

glomerular: blood filtered by hydrostatic pressure
normal >90
tubular: reabsorption (tubules to capillaries); secretion (capillaries to tubules)
secrete H+

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9
Q

Kidney function: excrete waste

A

filtration, reabsorption, secretion
form urine (glomerulus filtration, tubular reabsorption and secretion)

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10
Q

Kidney function: control BP and RBC production

A

renin-angiotensin-aldosterone
RBC: erythropoietin
decrease renal blood flow

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11
Q

Activate Vit D

A

convert form food/sun to active form that body needs

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12
Q

Acid-base balance

A

bicarbonate reabsorb
H+ secreted

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13
Q

Blood Urea Nitrogen (BUN)

A

normal 10-20 mg/dL

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14
Q

Creatinine (Cr)

A

normal 0.5-1.2 mg/dL

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15
Q

Glomerular filtration rate (GFR)

A

normal >90
changes with age
decrease when older

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16
Q

Renal/urologic concerns: urinary tract obstruction

A

interference with the flow of urine (stones)
severity by location and duration

17
Q

Hydroureter

A

much urine in ureter

18
Q

Hydronephrosis

A

enlarge renal pelvis

19
Q

ureterohydronephrosis

A

dilation of renal pelvis + ureter

20
Q

Renal/urologic concerns: renal insufficiency (lower)

A

altered storing and emptying
neurogenic bladder (spinal cord)
obstruction (tumor/prostate)

21
Q

acute renal failure

A

rapid decline in GFR
alteration in secretion or reabsorption
elevated BUN, CR, oliguria (urine output <30 ml/h or <400 ml/day)

22
Q

Pre-renal

A

most common

23
Q

Intrarenal acute renal failure

A

acute tubular necrosis is the most common cause

24
Q

postrenal ARF

A

with UTO that effects both kidneys

25
Q

initiation phase

A

oliguric <30 ml/h, <400 ml/day for 1-3 weeks
increase BUN + Cr

26
Q

Maintenance phase

A

diuresis-damage nephron
increase urine output
>600 ml/day

27
Q

Recovery phase

A

3-12 months
function returns
BUN+Cr return to WNL

28
Q

Acute Renal Failure Reasons

A

drug toxicity (antibiotics, NSAID)
hemodynamic: shock, liver failure; infection

29
Q

Chronic Renal Failure Reasons

A

diabetes, hypertension, chronic glomerulonephritis, atherosclerosis

30
Q

Chronic Renal Failure

A

irreversible loss of renal function that effects nearly all organ systems

31
Q

Anatomical changes (age)

A

70s: 50% loss of functioning glomeruli

32
Q

Physical changes (age)

A

decrease renal blood flow
decrease GFR, CrCl
Increase BUN + Cr
decrease ability to concentrate urine
altered excretion of water, NA, K, acid