RENAL ANAPHY Flashcards
functional units of kidneys
nephron
2 types of nephrons
- cortical nephrons
- juxtamedullary nephrons
nephrons that remove the wastes, reabsorbs the essential substances
cortical nephrons
nephrons responsible for the concentration of urine
juxtamedullary nephrons
blood flow through kidney (7)
renal artery afferent arteriole glomerular capillaries efferent arterioles peritubular capillaries vasa recta renal vein
functions of kidney (3)
- removal of metabolic waste
- regulation of water and electrolytes
- maintenance of acid-base balance
normal blood pH
7.35-7.45
3 phases of urine formation
- glomerular filtration
- tubular reabsorption
- tubular secretion
2 components of glomerulus
- 8 capillary lobes
- glomerular filtration barrier
3 parts of glomerular filtration barrier
- endothelial cells (capillary wall)
- glomerular basement membrane
- podocytes (bowman’s capsule)
2 functions of glomerular filtration barrier
- prevents the passage of HMW solutes (limit: <70 000 daltons)
- “shield of negativity” repels (-) molecules
glomerular filtrate specific gravity
1.010
serves as a nonselective filter of plasma substance
glomerulus
3 factors that affect filtration
- cellular structure of capillary walls
- hydrostatic and oncotic pressure
- renin-angiotensin-aldosterone system
pressure exerted by plasma proteins; pulls the solutes into the capillaries
give example
oncotic pressure
ex: albumin