RENAL ANAPHY Flashcards
functional units of kidneys
nephron
2 types of nephrons
- cortical nephrons
- juxtamedullary nephrons
nephrons that remove the wastes, reabsorbs the essential substances
cortical nephrons
nephrons responsible for the concentration of urine
juxtamedullary nephrons
blood flow through kidney (7)
renal artery afferent arteriole glomerular capillaries efferent arterioles peritubular capillaries vasa recta renal vein
functions of kidney (3)
- removal of metabolic waste
- regulation of water and electrolytes
- maintenance of acid-base balance
normal blood pH
7.35-7.45
3 phases of urine formation
- glomerular filtration
- tubular reabsorption
- tubular secretion
2 components of glomerulus
- 8 capillary lobes
- glomerular filtration barrier
3 parts of glomerular filtration barrier
- endothelial cells (capillary wall)
- glomerular basement membrane
- podocytes (bowman’s capsule)
2 functions of glomerular filtration barrier
- prevents the passage of HMW solutes (limit: <70 000 daltons)
- “shield of negativity” repels (-) molecules
glomerular filtrate specific gravity
1.010
serves as a nonselective filter of plasma substance
glomerulus
3 factors that affect filtration
- cellular structure of capillary walls
- hydrostatic and oncotic pressure
- renin-angiotensin-aldosterone system
pressure exerted by plasma proteins; pulls the solutes into the capillaries
give example
oncotic pressure
ex: albumin
pressure exerted by certain fluids; pushes the fluids/solutes out of the capillaries
give example
hydrostatic pressure
ex: water
cellular mechanisms involved in tubular reabsorption (2)
- active transport
- passive transport
major site of reabsorption, how many percent?
proximal convoluted tubule, 65%
tubular reabsorption:
sodium
mechanism:
location:
active - pct and dct
passive - ascending loop of henle
A-ct and P-aloh
tubular reabsorption:
water
mechanism:
location:
passive - pct, descending loop of henle, collecting ducts
phase of urine formation where we remove waste products and regulates acid-base balance
tubular secretion
where is H+ and NH3 secreted?
PCT, DCT, collecting tubule
where is urea secreted?
loop of henle
urine composition
95% water
5% solutes
urine primary organic compound
urea
urine primary inorganic compound
chloride
what tests might be used to assess whether the fluid is most likely urine?
urea and creatinine