HARR (CSF-SER-SYN) Flashcards
1
Q
1. Cerebrospinal fluid (CSF) is formed by ultrafiltration of plasma through the: A. Choroid plexus B. Sagittal sinus C. Anterior cerebral lymphatics D. Arachnoid membrane
A
A
2
Q
- Which statement regarding CSF is true?
A. Normal values for mononuclear cells are higher
for infants than adults
B. Absolute neutrophilia is not significant if the
total WBC count is less than 25/μL
C. The first aliquot of CSF should be sent to the
microbiology laboratory
D. Neutrophils compose the majority of WBCs in
normal CSF
A
A
3
Q
- When collecting CSF, a difference between
opening and closing fluid pressure greater than
100 mm H2O indicates:
A. Low CSF volume
B. Subarachnoid hemorrhage
C. Meningitis
D. Hydrocephalus
A
A
4
Q
- Which of the following findings is consistent
with a subarachnoid hemorrhage rather than a
traumatic tap?
A. Clearing of the fluid as it is aspirated
B. A clear supernatant after centrifugation
C. Xanthochromia
D. Presence of a clot in the sample
A
C
5
Q
5. The term used to denote a high WBC count in the CSF is: A. Empyema B. Neutrophilia C. Pleocytosis D. Hyperglycorrhachia
A
C
6
Q
- Which of the adult CSF values in the following
table are consistent with bacterial meningitis?
A. WBC: 50/uL; LYM: 44%; MON: 55%; EO: 0%; NEU: 0%; NED cells: 1%
B. WBC: 300/uL; LYM: 75%; MON: 21%; EO: 3%; NEU: 0%; NED cells: 1%
C. WBC: 2,000/uL; LYM: 5%; MON: 15%; EO: 0%; NEU: 80%; NED cells: 0%
D. WBC: 2,500/uL; LYM: 40%; MON: 50%; EO: 0%; NEU: 10%; NED cells: 0%
A
C
7
Q
- Given the following data, determine the corrected
CSF WBC count.
CSF RBC: 6,000/uL
PBS RBC: 4.0x10^6/uL
CSF WBC: 150/uL
PBS WBC: 5.0x10^3/uL
A. 8 WBC/μL
B. 142 WBC/μL
C. 120 WBC/μL
D. 145 WBC/μL
A
B
8
Q
- SITUATION: What is the most likely cause of the
following CSF results?
CSF glucose: 20mg/dL
CSF protein: 200mg/dL
CSF lactate: 50mg/dL (NV: 5-25mg/dL)
A. Viral meningitis
B. Viral encephalitis
C. Cryptococcal meningitis
D. Acute bacterial meningitis
A
D
9
Q
- Which of the following conditions is most often
associated with normal CSF glucose and protein?
A. Multiple sclerosis
B. Malignancy
C. Subarachnoid hemorrhage
D. Viral meningitis
A
D
10
Q
- The diagnosis of multiple sclerosis is often based
upon which finding?
A. The presence of elevated protein and low glucose
B. A decreased IgG index
C. The presence of oligoclonal bands by
electrophoresis
D. An increased level of CSF β microglobulin
A
C
11
Q
11. Which of the following results is consistent with fungal meningitis? A. Normal CSF glucose B. Pleocytosis of mixed cellularity C. Normal CSF protein D. High CSF lactate
A
B
12
Q
12. In what suspected condition should a wet prep using a warm slide be examined? A. Cryptococcal meningitis B. Amoebic meningoencephalitis C. Mycobacterium tuberculosis infection D. Neurosyphilis
A
B
13
Q
- Which of the following CSF test results is most
commonly increased in patients with multiple
sclerosis?
A. Glutamine
B. Lactate
C. IgG index
D. Ammonia
A
C
14
Q
- Which of the following is an inappropriate
procedure for performing routine CSF analysis?
A. A differential is done only if the total WBC
count is greater than 10/μL
B. A differential should be done on a stained CSF
concentrate
C. A minimum of 30 WBCs should be differentiated
D. A Wright’s-stained slide should be examined
rather than a chamber differential
A
A
15
Q
- Which cell is present in the CSF in greater
numbers in newborns than in older children
or adults?
A. Eosinophils
B. Lymphocytes
C. Monocytes
D. Neutrophils
A
C
16
Q
16. Neutrophilic pleocytosis is usually associated with all of the following except: A. Cerebral infarction B. Malignancy C. Myelography D. Neurosyphilis
A
D