Renal amyloidosis. Lupus nephropathy.

Question 1

What is renal amyloidosis?

Answer 1

• hereditary disorder - autosomal dominant
• misfolded proteins (amyloid) accumulates in the kidney
• causes proteinuria and/or hypertension followed by progressive kidney failure
• depending on the specific genotype it can affect other organs such as GI tract, liver, spleen, heart and skin