Nephrotic syndrome. Nephritic syndrome.

Question 1

What is nephrotic syndrome?

Answer 1

• a combination of nephrotic range proteinuria and a low serum albumin level and edema.
• can be primary or secondary
• Nephrotic syndrome can be primary, being a disease specific to the kidneys, or it can be secondary, being a renal manifestation of a systemic general illness.
• in all cases, injury to glomeruli is an essential feature
• Kidney diseases that affect tubules and interstitium, such as interstitial nephritis, will not cause nephrotic syndrome.

Question 2

What is Nephritis syndrome?

Answer 2

• clinical syndrome taht presents as hematuria, elevated blood pressure, decreases urineoutput, and edema.
• The major underlying pathology is inflammation of the glomerulus that results in nephritic syndrome.

Question 3

How to tell teh difference between nephrotic and nephritic syndrome?

Answer 3

In nephritic syndrome, you’d expect urine sediment with red cells, white cells, and protein, but not to the same level as you see with nephrotic syndrome.

The patient usually has a more prominent creatinine elevation and hypertension as well.