renal amk Flashcards

1
Q

causes of increased serum potassium

A
MACHINE 
M- medications such as ACEI and NSAIDS 
A- acidosis 
C- cellular destrcution like burns 
H - haemolysis and hypoaldosteronism 
I- intake - excessive 
N - nephrons, renal failure 
E - excretion - impaired
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2
Q

how do loop diuretics work and some examples

A

act by inhibiting the NKCC cotransporter in thick ascending limb of henle reducing absorption of NaCl

furosemide and bumetnaide

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3
Q

adverse effects of loop diuretics

A
hypotension 
hyponatraemia 
hypokalaemia 
hypomagnesamia 
hypochoraemic alkalosis 
hypoclacaemia
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4
Q

when do you use a loop diuretic

difference when to use IV or oral

A

heart failure - if acute IV and if chronic PO

resistant hypertension - particularly in patients with renal impairment

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5
Q

from anterior to posterior, what is the correct order of the structures entering the hilum

A

vein artery ureter

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6
Q

3 constrictions of ureter

A

leaving the kidney at the uteropelvic junction L1
bifurcation of the common iliac at L4
entering the bladder at the uterovesical junction

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7
Q

what is urge incontinence

A

overactivity of detrusor
overreactive bladder
feeling of urge to pass urine with a sudden urge

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8
Q

what is stress incontinence

A

pelvic floor consists of a sling of muscles that support contents of the pelvic floor - urethral, vaginal and rectal canals
urine leaks as bladd under pressure so leaks when coughing or laughing

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9
Q

overflow incotnience

A

chronic urinary retention or obstruction - men - unable to fully empty

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10
Q

total icnotnince

A

unable to store any urine

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11
Q

how to manage urge incontinence

A
bladder retaining , anticholergenic medication like oxybutynin ( side effect though of memory and dry ) 
or miabegron ( don't use in hypertension ) as alternative
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12
Q

how to manage stress incontinence

A

avoid caffeine, pelvic floor exercises , fluoxetine is antidepressant could also have vaginal free tape and coposuspensuoon

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13
Q

what bacteria most commonly causes UTI

A

Ecoli - gram negative rod

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14
Q

when are UTIs considered recurrent

A

UTIs are considered recurrent after at least two episodes within 6 months or three or more episodes within 12 months.

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15
Q

what can be caused from a partially treated UTI , chlamydia or appendicitis and renal stones

A

sterile pyuria

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16
Q

calcium oblate stones what shape

A

1: Diamond-shaped or rhomboid-shaped crystals are characteristic of stones consisting of uric acid. These are prevalent in individuals with hyperuricemia.
2: Envelope-shaped crystals are typical of calcium oxalate stones. low water-intake. Dehydration predisposes to the precipitation of calcium oxalate into stones.
3: Hexagonal-shaped crystals are found in cystine stones.
4: Coffin-lid crystals are characteristic of ammonium magnesium phosphate stones.
5: Wedge-shaped prism crystals are found in calcium phosphate stones and are the second most common types of calcium stones, after calcium oxalate stones.

17
Q

pneumonia structures that are retroperitoneal

A

S: suprarenal (adrenal) gland

A: aorta/IVC

D: duodenum (second and third part)

P: pancreas (except tail)

U: ureters

C: colon (ascending and descending)

K: kidneys

E: oesophagus

R: rectum

18
Q

Hyperlipidaemia

A

Hyperlipidaemia is the term used to denote raised serum levels of one or more of total cholesterol (TChol), low-density lipoprotein cholesterol (LDL-C), triglycerides (TGs), or both TChol and TG (combined hyperlipidaemia

19
Q

what is raised disproportionality in pancreatitis

A

Amylase is produced in the pancreas and is used to digest carbohydrates. It is released into the blood in large quantities in pancreatic disease

20
Q

when is ALT high

A

Alanine aminotransferase (ALT) is a relatively liver-specific cytoplasmic enzyme and is raised in hepatic injury.

21
Q

when is ALP high

A

Alkaline phosphatase (ALP) is found predominantly in the biliary tree and hepatic epithelial cells. It is commonly raised significantly in obstructive liver diseases.- bile duct disruption

22
Q

when GGT high

A

Gamma-glutamyltransferase (GGT) is commonly raised by alcohol or drugs (for example phenytoin).

23
Q

causes of acute pancreatitis

A

Popular mnemonic is GET SMASHED
Gallstones
Ethanol
Trauma
Steroids
Mumps (other viruses include Coxsackie B)
Autoimmune (e.g. polyarteritis nodosa), Ascaris infection
Scorpion venom
Hypertriglyceridaemia, Hyperchylomicronaemia, Hypercalcaemia, Hypothermia
ERCP
Drugs (azathioprine, mesalazine*, didanosine, bendroflumethiazide, furosemide, pentamidine, steroids, sodium valproate)