Renal Flashcards
Site of action for thiazide diuretics
Distal convoluted tubule’s
Site of action for a loop diuretics
Ascending loop of Henle
Site of action for aldosterone antagonist a.k.a. potassium sparing diuretics
Distal convoluted tubule’s and collecting duct
Laboratory results suggestive of pre-renal conditions include
Urine sodium less than 25
urine osmolality greater than 500 fractional excretion of sodium less than 1%
fractional excretion of urea less than 35%
BUN: creatinine ratio greater than 15
Laboratory results suggestive of intrinsic renal disease
Urine sodium greater than 40
urine osmolality between 200 to 300 fractional excretion of sodium greater than 3%
fractional excretion of urea greater than 50%
BUN creatinine ratio less than 15
Respiratory Acidosis
PaCo2 changes correlation with Ph
Acute: 1mm HG increase causes .008 decrease in Ph.
Chronic: 1mm Hg increase in PaCo2 causes . 003 decrease in Ph
Respiratory acidosis metabolic compensation
Acute for every 10 mm of Hg increase in PaCO2 the bicarbonate increases by one milliequivalents per liter.
Chronic for every 10 mmHg increase in PACO2 the bicarbonate increases by 5 mEq per liter
EKG changes with hypocalcemia ?
Prolong QT interval
EKG changes with hypercalcemia ?
Prolonged PR interval , short QT , wide QRS