Renal Flashcards

1
Q

Site of action for thiazide diuretics

A

Distal convoluted tubule’s

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2
Q

Site of action for a loop diuretics

A

Ascending loop of Henle

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3
Q

Site of action for aldosterone antagonist a.k.a. potassium sparing diuretics

A

Distal convoluted tubule’s and collecting duct

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4
Q

Laboratory results suggestive of pre-renal conditions include

A

Urine sodium less than 25
urine osmolality greater than 500 fractional excretion of sodium less than 1%
fractional excretion of urea less than 35%
BUN: creatinine ratio greater than 15

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5
Q

Laboratory results suggestive of intrinsic renal disease

A

Urine sodium greater than 40
urine osmolality between 200 to 300 fractional excretion of sodium greater than 3%
fractional excretion of urea greater than 50%
BUN creatinine ratio less than 15

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6
Q

Respiratory Acidosis

PaCo2 changes correlation with Ph

A

Acute: 1mm HG increase causes .008 decrease in Ph.
Chronic: 1mm Hg increase in PaCo2 causes . 003 decrease in Ph

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7
Q

Respiratory acidosis metabolic compensation

A

Acute for every 10 mm of Hg increase in PaCO2 the bicarbonate increases by one milliequivalents per liter.
Chronic for every 10 mmHg increase in PACO2 the bicarbonate increases by 5 mEq per liter

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8
Q

EKG changes with hypocalcemia ?

A

Prolong QT interval

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9
Q

EKG changes with hypercalcemia ?

A

Prolonged PR interval , short QT , wide QRS

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