renal 4 Flashcards

1
Q

metabolism produces

A

h ions

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2
Q

gain H; lose H

A

kidney ;urine

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3
Q

buffer for H

A

bicarb

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4
Q

resp acidosis

A

accum of CO2 which makes H

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5
Q

any problem with ventilation

A

inc CO2

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6
Q

diabetics and hypoxia

A

produce acid

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7
Q

normal diet

A

make diet

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8
Q

net exogenous acid production

A

acid made from protein digestion and diabetes and hypoxia

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9
Q

tf amt of acid in body is less than ingest per day

A

true

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10
Q

tf most of bicarb reabsorption occurs in prox tubule an none goes into urine

A

t

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11
Q

tf bicarb is reabsorbed at all parts of renal tubule

A

t

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12
Q

at the prox tubule — bicarb is reabs and — h+ is secreter

A

1;1

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13
Q

prox tubule luminal mebrane how do you get H+ out into lumen

A

thru exchanger(with NA) and pumP

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14
Q

how does HCO3 get to cap at basolat membrane of Prox tubule

A

cotransport with NA

exchange with Cl

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15
Q

tf in prox tubule and collecting duct

h secreted and HCO3 reabsorbed

A

t

and both 1;1

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16
Q

at luminal side of the collecting duct

H get secreted by

A

pump with H+

and exchange with K(need ATP)

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17
Q

how does hco3 get to cap side in CD

A

exchange with CL

18
Q

intercalated alpha type cell occurs

A

at CD to resorb bicarb

19
Q

principal cells have wat features

A

aqp2 and Na channel

located in CD

20
Q

interacalated cells

21
Q

beta intercalated types cells are used to

A

transfer hco3 to tube in alkalosis(excess hco3 in blood)

22
Q

purpose of interacalated alpha; vs beta cells

A

reabsorb bicarc; secrete bicarb

23
Q

in intercalated beta cells of the cd

hco3 secreted in eaxchanged for

24
Q

reabs H+ and secretion of Bicarb occurs in

interacalate alpha

intercalated beta

prox tubule

A

intercalated beta

25
exhange of h with urinary buffer
h+ with atp pump bicarb exchange for CL
26
tf ammonium production and bicarb reabsorption are 1;1 in the proximla tubule (h excretion from urine)
T
27
NH4 reabsorbs ----- and get resecreted as -----
at thick ascending limb nh3 in the collecting duct
28
contributes to 2/3 of acid excretion from urine
ammonium production
29
tf ammonium production to excrete acids in urine is ridge and take up 2/3 of total acid excretion in urine
f flexible 2/3 correct
30
during ammonium formation to excrete acid in urine glut braks down to bicarb and nh4(1;1) nh4 dissolves away to tubular fluid alone nh3 is exchanged for na on the tub. membrane
glut braks down to bicarb and nh4(1;1)
31
renal failure
patient cant get rid of acid
32
diabetic acidosis
inc nh4 and ta in cap
33
acidosis
inc in acid in tubular cells
34
what does acidosis trigger
transporter and enzyme secretion to transport acids(nh4 and TA) to urine
35
excersizing
met. acidosis
36
diahrreha
met. acidosis
37
vomit
met. alkalosis
38
trigger hypervent
met acid.
39
trigger hypovent
met. alk.
40
tf metabolic acidosis results in low ph and high pCO2
F low both
41