renal 3 Flashcards
vol of ecf reg by
amt of salt in body
most of Na available in
ECF
pressure or vol inc from Na are detected by
baroreceptors
responce of baroreceptors to inc(pressure or vol)
tell kidney to excrete salt
load dependent
more Na filtered more resorbed Proxt tubule and Thick ascending limb
maintain intak=excretion
distal tube and CD
limited capacity for resorption of NA
distal tube and CD
tf when u gain or lose NA the first site to be affected is distal segment
T
tf when there is loss of salt then more na is resorbed in the prox tubule
T
NO acts in NA constraction stimulates na resorption at prox tubulte inh na resorbtion at prox tubule
inh na resorbtion at prox tubule happens when NA inc(ecf expansion)
tf symp and ang1 stimulate na resorption at prox tubule when there is loss of NA
F symp and ang2
tf NA amt reabsorbed in distal tubule is low
F small percent but large amt
which of the following doesnt inh. resorption of NA at distal tubule? no PG ANP ALdosterone
aldosterone inc NA absorption when Na is intaken(ecf expansion)
which of the function is function of aldoesteron Na resorption by kidney inc adh sec and leads to water retention more thirst arteriolar vasoconstrictor(restore BP)
Na resorption by kidney other by Ang 2
which of following reg how much aldosterone secreted in plasma renin ang1 ang 2 angiotensinogen
renin
renin released
from granular cells
ANP
inc in high ecf cases(NA intake)
TF RAA system inc na excretion
f dec it
h20 reabs in prox tubule is
isoosmotic follows NA
tf most of water is reabsorbed at prox tubule anddistal tubule
F distal tubule is imperm to water
tf passive transport maintain 200 mOsm gradient in the medulle between tubules cells and int fluid
f active transport
equilibrates with interstitial fluid
descending limb
oblig water loss
.5l / day
diuresis
low adh
in diuresis osmomolarity is more in cd osmolarity in less in cs salt cant be reabrorb in CD
osmolarity in less in cs because salt is reabsorbed in CD
active transport out of ascending limb
concentrate the interstitium
action of ADH to reabsorb water at CD needs
loop of henle needed to set up stage of concentrating interstitium
wat helps maintain int. molarity
vasa recta
adh constrict —-,; results in—- solute in medulla
vasa recta; less
adh sec by
post pit
tf to restore osmolarity osmorecptors alone are adequate to inc adh
f need to drink h2o
tf baroreceptor only inh ADH receptors when you have inc vol
f they are constantly inhibiting ADH receptors
tf osmorecptor and baroreceptor both both have adh as effectors
t
vol receptor
baroreceptor
sense plasma osmolality
osmoreceptor
ecf expansion and anp
inh thirst and adh release
