Relevance of Hep B & C Flashcards
How is Hep A transmitted
Faecal-oral
How is Hep D transmitted
Parenteral, sexual
How is Hep E transmitted
Faecal-oral route
Which Hepatitis’ have a vaccine
Hep A,B,E
Which virus has a relationship with Hep B
Hepatitis D requires Hep B for replication
When and who discovered Hep B
1960s by Baruch S. Blumberg
What family was HBV a first member of
Hepadnaviridae
What largest particle is found in the blood of an infected Hep B patient
Dane particle
What is found in addition to dane particles
Sperical particles and filamentous forms
What is HBs Ag
Hepatitis B surface antigen
What is HBc Ag
Hepatitis B core antigen
How long can HBV surface in dry blood
1 week or more
What are the modes of transmission of Hep B
Parenteral
Sexual
Perinatal
What is the incubation period of Hep B
2-3 months
If symptomatic what symptoms may a person with Hep B display
Flu like illness possibly with a yellow tone of the skin or sclera of the eyes
What is the first viral marker of Hep B to appear
HBsAg
What is the difference between normal recovery and chronic carriage of Hep B
Normal:
Clearance of antigens and creation of Anti-HBs within 6 months
Chronic:
HBsAg persists and no development of Anti-HBs
How is chronic Hep B defined
Persistence of HBsAg and failure to develop HBsAb more than 6 months after infection
What will be detected in the Hep B test of an acute infected patient
IgM anti-core (+ve) HBsAg (+ve)