skin and soft tissue infections Flashcards

1
Q

What is a virulence factorof S.aureus

A

Panton valentine
Leukocidin toxin

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2
Q

What is a disease caused by S.aureus

A

Angular chelitis

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3
Q

What is an example ofa cirulence factor of the bacteria S.pyogenes

A

Superantigens and toxic shock syndrome

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4
Q

What is the other name for S.pyogenes

A

GroupA streptococci

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5
Q

What causes the disease cellulitis

A

S.pyrogenes/streptococci A

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6
Q

What is a virulence factor of S.anginosus

A

Intermedilysin (cytotoxin leads to lysis of the cells)

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7
Q

What are the virulence factors of anaerobes

A

Alpha toxin (lecithinase - breaks down cell membranes)

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8
Q

What is the nagler reaction

A

Used to detect alpha toxin virulence factor

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9
Q

What microbe causes gas gangrene

A

Anaerobes

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10
Q

What is a herpessimplex virulence factor

A

Cell lysis

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11
Q

What is a virulence factor of candida albicans

A

Phospholipase - breaks down phospholipids

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12
Q

What disease does candida albicans cause

A

oral candidosis (erythematous)

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13
Q

What infections affect the epidermis

A

Impetigo
Angular chelitis

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14
Q

What disease affects the dermis

A

Erysipelas - appears as a butterfly rash on face

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15
Q

What causes impetigo

A

S.pyrogenes

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16
Q

What causes erysipelas

A

S.pyrogenes

17
Q

What diseases affect the subcutaneous

A

Cellulitis - S.pyrogenes/staph aureus

18
Q

What disease affects the fascia skin layer

A

Necrotising fasciitis - S.aureus/S.pyrogenes

19
Q

Which infections affect muscle

A

Myonecrosis/gangrene

20
Q

What pathogens cause bite wound infections

A

Human: mixed anaerobes
Animal: Pasteurella Multicoda

21
Q

What are the treatment principles of soft tissue infections

A

Diagnosis
Surgical debridement
Microbiological specimens
Antibiotics
Review

22
Q

How is S.aureus MRSA treated

A

Meticillin sensitive - flucloxacillin
Meticillin resistant - vancomycin

23
Q

What antibiotic is used for S.pyrogenes

A

Penicillin

24
Q

How is S.anginosus treated

A

Penicillin

25
Q

How is severe odontogenic infection treated

A

Hospital treatment to include IV Ben Pen and metronidazole

26
Q

What antibiotic is prescribes for dental abscesses

A

Penicillin V