skin and soft tissue infections Flashcards
What is a virulence factorof S.aureus
Panton valentine
Leukocidin toxin
What is a disease caused by S.aureus
Angular chelitis
What is an example ofa cirulence factor of the bacteria S.pyogenes
Superantigens and toxic shock syndrome
What is the other name for S.pyogenes
GroupA streptococci
What causes the disease cellulitis
S.pyrogenes/streptococci A
What is a virulence factor of S.anginosus
Intermedilysin (cytotoxin leads to lysis of the cells)
What are the virulence factors of anaerobes
Alpha toxin (lecithinase - breaks down cell membranes)
What is the nagler reaction
Used to detect alpha toxin virulence factor
What microbe causes gas gangrene
Anaerobes
What is a herpessimplex virulence factor
Cell lysis
What is a virulence factor of candida albicans
Phospholipase - breaks down phospholipids
What disease does candida albicans cause
oral candidosis (erythematous)
What infections affect the epidermis
Impetigo
Angular chelitis
What disease affects the dermis
Erysipelas - appears as a butterfly rash on face
What causes impetigo
S.pyrogenes
What causes erysipelas
S.pyrogenes
What diseases affect the subcutaneous
Cellulitis - S.pyrogenes/staph aureus
What disease affects the fascia skin layer
Necrotising fasciitis - S.aureus/S.pyrogenes
Which infections affect muscle
Myonecrosis/gangrene
What pathogens cause bite wound infections
Human: mixed anaerobes
Animal: Pasteurella Multicoda
What are the treatment principles of soft tissue infections
Diagnosis
Surgical debridement
Microbiological specimens
Antibiotics
Review
How is S.aureus MRSA treated
Meticillin sensitive - flucloxacillin
Meticillin resistant - vancomycin
What antibiotic is used for S.pyrogenes
Penicillin
How is S.anginosus treated
Penicillin
How is severe odontogenic infection treated
Hospital treatment to include IV Ben Pen and metronidazole
What antibiotic is prescribes for dental abscesses
Penicillin V
