Regulation of Metabolism Flashcards

1
Q

Specific Activity

A

Measure of enzyme kinetics, per unit of mass

rate of reaction of an enzyme and substrate

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2
Q

Percentage Recovery

A

Final Value/Initial Value * 100

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3
Q

Homeostasis

A

Maintenance of internal stability

regulation of enzyme activity aiding metabolic functions

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4
Q

Regulatory strategies

A

Control:

  • Amount of enzyme present
  • Activity of enzyme present
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5
Q

Control of enzyme activity

A
  • Allosteric control
  • Multiple enzyme variations
  • Reversible covalent modifications
  • Proteolytic activation
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6
Q

Allosteric Control

A
  • Regulatory sites on enzymes

- Cooperativity: allosteric activity induces conformational change in shape

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7
Q

Multiple Enzyme Variation

A
  • Isoenzymes: Slightly varied structure

- Fine-tunes metabolism

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8
Q

Covalent Modifications

A
  • Reversible
  • Activation/Inhibition
  • Localisation
  • Degradation
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9
Q

proteolytic Activation

A

Zymogen: Inactivated enzyme

Examples:

  • Blood Ccoting
  • Digestive enzymes
  • Programmed cell death
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