REGULATION OF ENZYME ACTIVITY

Question 1

is an enzyme with two or more protein chains (quaternary
structure) and two kinds of binding sites (substrate and regulator

Answer 1

allosteric enzyme

Question 2

increases enzyme activity; the shape of the active site is
changed such that it can more readily accept substrate

Answer 2

positive regulator

Question 3

(a noncompetitive inhibitor) decreases enzyme activity; changes to the active site are such that substrate is less readily accepted

Answer 3

negative regulator

Question 4

is a process in which activation or inhibition of the first reaction in a reaction sequence is controlled by a product of the reaction sequence.

Answer 4

Feedback control

Question 5

is often used to describe a process in which a regulatory molecule that binds at one site in an enzyme influences substrate binding at the active
site in the enzyme

Answer 5

Allosteric control

Question 6

is an enzyme that catalyzes the breaking of
peptide bonds that maintain the primary structure of a protein

Answer 6

A proteolytic enzyme

Question 7

is the inactive precursor of a proteolytic enzyme.
(An alternative, but less often used, name for a zymogen is proenzyme

Answer 7

zymogen

Question 8

is a process in which enzyme activity is altered by
covalently modifying the structure of the enzyme through attachment of a chemical group to or
removal of a chemical group from a particular amino acid within the enzyme’s structure.

Answer 8

Covalent modification