MODELS OF ENZYME ACTION Flashcards
is the relatively small part of an enzyme’s structure that is actually involved in catalysis.
active site
three-dimensional entity formed by groups that come
from different parts of the protein chain(s); these groups are brought together by the
Folding and bending
location in the enzyme
“crevicelike”
is the intermediate reaction species that is formed when a
substrate binds to the active site of an enzyme
enzyme–substrate complex
he active site in the enzyme has a fixed, rigid geometrical conformation.
Lock-and-Key Model
allows for small changes in the shape or geometry of the
active site of an enzyme to accommodate a substrate
Induced-Fit Model
The forces that draw the substrate into the active site are many of the same forces
that maintain tertiary structure in the folding of peptide chains
Electrostatic interactions and hydrophobic interactions