Regulation CH 3.4

Question 1

Irreversible Inhibition

Answer 1

an inhibitor covalently binds to the amino acid side chain at the active site of an enzyme and permanently deactivated the enzyme.

Question 2

Reversible inhibitor

Answer 2

an inhibitor noncovalently binds to an active site but doesn’t create the chemical reaction to completely deactivate the enzyme.

Question 3

Competitive Inhibitor

Answer 3

a molecule that competes with the substrate for a spot in the active site, this inhibition is reversible

Question 4

Noncompetitive Inhibitor

Answer 4

binds to an enzyme at a site different from the active site. The binding changes the shape of the enzyme which alters its activity.

Question 5

Allosteric Regulation

Answer 5

non-substrate molecule binds or modifies a site other than the active site of an enzyme (allosteric site)

Question 6

Two different types of Modification

Answer 6

Covalent modification

Noncovalent bonding

Question 7

Feedback Inhibition

Answer 7

the end product is present at a high concentration and some of it binds to a site on the commitment step enzyme which deactivates the enzyme.

Question 8

Environmental affects on Enzymes

Answer 8

pH and temperature