Reducing and Enlarging Formulas Flashcards

1
Q

From the following formula for 40 sertraline capsules, calculate the factor that would be used if a pharmacist wished to prepared 250 capsules.
Sertraline Hydrochloride 300 mg
Silica Gel 6 g
Calcium Citrate 4 g

A

The correct answer is:

6.25

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2
Q
From the following formula,
calculate the quantity of propylene glycol required to make 5 lb. of hydrophilic ointment 
Methylparaben 0.25 g
Prophylparaben 0.15 g
Sodium lauryl sulfate 10   g
Propylene glycol 120 g
Stearyl alcohol 250 g
White petrolatum 250 g
Purified water, to make             1000 g
A

The correct answer is:

272.4 g

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3
Q
From the following formula,
calculate the quantity of propylparaben required to make 5 lb. of hydrophilic ointment
Methylparaben 0.25 g
Prophylparaben 0.15 g
Sodium lauryl sulfate 10   g
Propylene glycol 120 g
Stearyl alcohol 250 g
White petrolatum 250 g
Purified water, to make             1000 g
A

The correct answer is:

0.3405 g

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4
Q
Calculate the amount of Erythromycin needed to prepare 150mL of the following ophthalmic solution:
Erythromycin lactobionate 500 mg
Dexamethasone Sodium Phosphate 100 mg
Glycerin 2.5 mL
Sterile Water for Injection, ad 1000 mL
A

The correct answer is:

75 mg

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5
Q
From the following formula,  calculate the quantity of sodium bicarbonate required to make 1500 g of the powder.
Calcium carbonate 5 parts
Magnesium oxide 1 part
Sodium bicarbonate 4 parts
Bismuth subcarbonate 3 parts
A

The correct answer is:

461.54 g

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6
Q

According to the literature, when the product Amevive (alefacept) is reconstituted with sterile water for injection to prepare 0.6 mL of injection, it contains the following in each 0.5 mL:
Alefacept 7.5 mg
Sucrose 12. 5 mg
Glycine 5 mg
Sodium Citrate 3.6 mg
Citric acid 0.06 mg
How much alefacept would be needed to manufacture a 5000 batch of vials for reconstitution?

A

The correct answer is:

37.5 g

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7
Q

Calculate the amount of coal tar solution required to make 30 g of ointment of the to the following formula:
Coal tar solution 12%
Hydrous wool fat 24%
Yellow soft paraffin to 100%

A

The correct answer is:

3.6 g

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8
Q

Calculate the amount of witch hazel required to make 3L of the formula:
Wicth hazel 4 parts
Glycerol 1 part
Water 15 parts

A

The correct answer is:

0.6 L

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9
Q

A medicated cream has the following formula:
Salicylic acid 1 part
Precipitated sulfur 9 parts
Aqeous cream 40 parts
Calculate the amount of salicylic acid if you start with 3.6 g of precipitated sulfur

A

The correct answer is:

0.4 g

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10
Q

The formula for a sports rub cream is given in the literature as follows:
Methyl salicylate 15 ml
Menthol 10 g
Eucalypus oil 1 g
Hydrophilic ointment ad 100 g
If the specific gravity of methyl salycilate is 1.18, how many grams of methyl salicylate would be needed to prepare a dozen 30-gram tubes of ointment.

A

The correct answer is:

63.72 g

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