Percentage, Ratio Strength and Other Expressions of Concentration (Part 1) Flashcards
At the end of the lesson, the students must have: 1. Executed computation skills in solving concentration of a solution in the way that is most appropriate for a problem or application; 2. Familiarized with the different units used to expressed the concentration of solutions; 3. Stated the relationship between the different methods of expressing concentrations of pharmaceutical preparations; 4. Converted one expressions of concentration to another.
expresses the number of grams of a constituent
in 100 mL of a solution or liquid preparation and it is used regardless whether water or another liquid in the solvent or vehicle.
Percent weight in volume (w/v)
Expressed as: ____% w/v.
expresses the number of milliliters of a constituent in 100 mL of a solution or liquid preparation.
Percent volume in volume (v/v)
Expressed as: ____% v/v.
expresses the number of grams of a constituent
in 100 g of solution or preparation.
Percent weight in weight (w/w)
Expressed as: ____% w/w.
The term percent, or the symbol %, when used without qualifications means:
For solutions or suspensions of solids in liquids;
percent weight in volume
Expressed as: ____% w/v.
The term percent, or the symbol %, when used without qualifications means:
For solutions of liquids in liquids;
percent volume in volume
Expressed as: ____% v/v.
The term percent, or the symbol %, when used without qualifications means:
For mixtures of solids or semi-solids;
percent weight in weight
Expressed as: ____% w/w.
The term percent, or the symbol %, when used without qualifications means:
For solutions of gases in liquids;
percent weight in volume
Expressed as: ____% w/v.
Solve the following:
1. Rx
Antipyrine 5%
Glycerin, ad 60
Sig: 5 drops in right ear
How many grams of antipyrine should be used in preparing the prescription?
Note: answer whole number space unit, abbreviated
The correct answer is: 3 g
What is the percentage strength (v/v) if 225 g of liquid (Sp gr 0.8 ) is added to enough water to make 1.5 L of the solution?
Note: answer should be in percent (%) and 2 decimal places, answer/space/unit
The correct answer is: 18.75 %
A metronidazole gel contains 0.75% of a drug in 70-g tubes. An applicator can hold 5 g of a gel for each administration. How much drug, in milligrams, will be contained in each application?
Answer: with one decimal place, answer/space/ unit abbreviated
The correct answer is: 37.5 mg
Aluminum chloride is soluble in 1 in 4 alcohol. How much aluminum chloride, in kilogram, can be dissolved in 1.6 L of alcohol?
Note: Answer is one decimal place only, answer/space/unit
The correct answer is: 0.4 kg
How much coal tar solution 2% w/v would contain 140 mg of coal tar?
Note: Answer is a whole number/space/unit
The correct answer is: 7 mL
Express 2 g of active ingredient in 250 mL of solution as ratio strength.
Note: No spaces between the number and the ratio sign
Lowest term
The correct answer is: 1:125
You require 90 mg of cocaine hydrochloride. How many milliliters of a 1:400 solution is equivalent to this amount?
Note: Answer is a whole number/space/unit
The correct answer is: 36 mL
Ster-Zac Bath Concentrate contains 2% triclosan and to prevent cross infection, 28.5 mL should be put in a bath. How much triclosan would the bath contain.
Note: answer should be two decimal places only/space/unit
The correct answer is: 0.57 g
Nerisona cream contains 0.1% w/w of difluocortolone valerate. How much difluocortolone valerate is contained in a 30-g tube?
The correct answer is: 30 mg
Marcain with adrenaline contains adrenaline as a strength stated as 1 in 200,000. Express this strength as a percentage.
Note: Answer should be 4 decimal places/ space / unit
The correct answer is: 0.0005 %
Acyclovir cream has a stated strength of 5% w/w . Express this strength as a ratio strength.
The correct answer is: 1:20
You dispense a 13.5 mL bottle of sodium cromoglicate at 2% eye drops. How much sodium cromoglicate, in milligram, does the bottle contain?
The correct answer is: 270 mg
A patient is dispensed a 10-mL bottle of chloramphenicol 5% ear drops . How much chloramphenicol, in milligram, is present in the bottle?
The correct answer is: 500 mg
A patient is dispensed a 10-mL bottle of chloramphenicol 5% ear drops . If there are 20 drops in 1 mL, how much chloramphenicol is there in each drop, expressed in micrograms.
Note: use the abbreviated unit mcg
The correct answer is: 250 mcg
If a liquid vitamin preparation contains 0.16 micrograms of vitamin B12 per 5 mL, what is the ratio strength of the preparation?
Separate thousand/millions with a comma
The correct answer is: 1:31,250,000