red ete Flashcards

1
Q

what are the two different reactions shown in the conjucitva in response to inflammation

A

the two reactions are follicles and papillae , follicles are collections of inflammatroy cells called lymphyocytes , appearing as white rice grain like structures , papillae on the other had present as exubrent red blood vessles giving the conjuctiva a velvety smooth and red apperance

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2
Q

How does meibomian gland dysfunction contribute to worsening symptoms of dry eye, particularly on awakening?

A

Meibomian gland dysfunction leads to unhealthy lipid secretion, causing poor tear film quality. During sleep, reduced blinking allows the unhealthy tear film to stagnate, exacerbating symptoms upon awakening.

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3
Q

What are the common tests used for diagnosing dry eye?

A

Common tests for diagnosing dry eye include the fluorescein eye drop test to assess tear film quality, Tear Film Break-Up Time (TFBUT) to evaluate tear film stability, and the Schirmer test to measure tear production.

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4
Q

What are some symptoms and presentations of blepharitis?

A

Symptoms of blepharitis include a gritty or foreign body sensation, watery eyes, and the presence of lumps or cysts on eyelid margins. Presentations may involve thickened red eyelashes, loss of eyelashes, and flaky material in the eyebrows.

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5
Q

How can you differentiate between viral and allergic conjunctivitis based on clinical presentation?

A

in viral conjunctivitis, white spots known as subepithelial infiltrates may appear in the cornea. Allergic conjunctivitis often presents with papillae due to an allergic reaction.

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6
Q

redness around the whole eye

A

diffuse redness

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7
Q

What is the significance of Hutchinson’s sign in herpes zoster ophthalmicus?

A

Hutchinson’s sign indicates the involvement of the nasociliary nerve in herpes zoster ophthalmicus. It suggests the potential presence of corneal ulcers or other complications due to varicella-zoster virus reactivation.

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8
Q

How does acute angle-closure glaucoma manifest clinically?

A

Acute angle-closure glaucoma presents with a sudden onset of severe eye pain, diffuse redness, hazy cornea, and a mid-dilated pupil due to increased intraocular pressure.

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9
Q

What are the three layers of tear film, and what is the function of each layer?

A

The three layers of tear film are the lipid layer (outermost), aqueous layer, and mucin layer (innermost). The lipid layer prevents evaporation, the aqueous layer provides moisture, and the mucin layer helps in adhering the tear film to the surface of the eye.

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10
Q

How does the Tear Film Break-Up Time (TFBUT) test help diagnose dry eye syndrome?

A

The TFBUT test involves observing how quickly dark spots appear in the tear film after instilling fluorescein. A shorter TFBUT time indicates instability of the tear film, suggesting dry eye syndrome.

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11
Q

What is the significance of the Schirmer test in diagnosing dry eye syndrome?

A

The Schirmer test measures tear production by placing a paper strip in the lower eyelid fornix. A lower wetness measurement indicates reduced tear production, which is indicative of dry eye syndrome.

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12
Q

What are some common viral causes of conjunctivitis, and how do they differ in presentation?

A

Common viral causes include herpes simplex virus and adenovirus. Herpes simplex virus may lead to dendritic ulcers, while adenoviral infections can present with subepithelial infiltrates in the cornea.

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13
Q

Describe the differences between adult inclusion conjunctivitis and neonatal conjunctivitis.

A

Adult inclusion conjunctivitis is typically sexually transmitted and presents with a red eye and discharge. Neonatal conjunctivitis occurs in infants due to exposure during childbirth and requires immediate treatment to prevent complications.

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14
Q

How do dendritic ulcers caused by herpes simplex virus differ from geographical ulcers?

A

Dendritic ulcers have a branch-like appearance due to the virus’s spread along corneal nerves, while geographical ulcers result from healed ulcers attracting blood vessels from the conjunctiva, potentially leading to poor vision.

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15
Q

What is the primary organism responsible for corneal ulcers in contact lens wearers, and how does it differ from other bacterial infections?

A

Acanthamoeba is the primary organism in contact lens-related corneal ulcers. Unlike other bacterial infections, it forms cysts and requires intensified treatment with both topical antibiotics and steroids.

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16
Q

What are the clinical features of acute anterior uveitis (iritis), and why is it important to investigate systemic associations?

A

Acute anterior uveitis presents with white dots (keratic precipitates) in the cornea and may be associated with conditions like inflammatory bowel disease or sarcoidosis, making it crucial to investigate systemic associations.

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17
Q

How can you differentiate between episcleritis and scleritis based on clinical findings?

A

Episcleritis presents with bright red blood vessels that blanch with vasoconstricting eye drops like phenylephrine. In contrast, scleritis causes deep, intense pain and is associated with systemic inflammation, potentially leading to sight-threatening complications.

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18
Q

What are the common causes and clinical presentations of eyelid malpositions?

A

Eyelid malpositions can result from conditions like entropion and ectropion, leading to eyelashes rubbing against the eye or exposure of the conjunctiva, respectively. Symptoms include redness, irritation, and foreign body sensation.

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19
Q

What is a subconjunctival hemorrhage, and what are its characteristics?

A

A subconjunctival hemorrhage is a benign condition characterized by the presence of blood under the conjunctiva. It typically presents as a painless, red patch on the white part of the eye.

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20
Q

What are the key differences between viral and bacterial conjunctivitis in terms of clinical presentation and management?

A

Viral conjunctivitis often presents with watery discharge and follicles, while bacterial conjunctivitis may have purulent discharge and papillae. Treatment for viral conjunctivitis is supportive, while bacterial conjunctivitis may require topical antibiotics.

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21
Q

How do corneal foreign bodies contribute to corneal abrasions, and what are the potential complications?

A

Corneal foreign bodies can cause corneal abrasions, leading to pain, redness, and foreign body sensation. Complications may include corneal infections or scarring if not promptly treated.

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22
Q

What are the clinical features and systemic associations of acute anterior uveitis (iritis)?

A

Acute anterior uveitis presents with eye pain, photophobia, and decreased vision. Systemic associations may include inflammatory bowel disease, psoriasis, or ankylosing spondylitis.

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23
Q

Differentiate between episcleritis and scleritis based on clinical findings and management.

A

Episcleritis presents with localized redness and discomfort that blanches with vasoconstrictors. Scleritis causes severe, deep pain and may be associated with systemic conditions. Management involves anti-inflammatory agents and treating underlying systemic diseases.

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24
Q

what medications make dry eye worse

A

oral histamines

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25
what are you looking for with the TFBUT with furoscein
how quickly the dark spots appear
26
misidirected eyelashes
trichaisis
27
presentation of chronic blepharitis affecting the meibomian gland
notching and smoothing of eyelids = gone because meibomian glands are blocked up - lid margins become red and poor tear film
28
treatment for blepharitis
lid hygiene clean lid margins (using warm water and clean lid margins) get rid of deposits from openings of the meibomian glands and makes them secreate better lubraicants for symptoms of dry eyes chloremphenicol for active infection topical steroids because its inflammation sometimes in children oral antibuotics (low dose) are given because they have an antiinflammatory effect acts as an anti-inflammatroy not an antibiotic
29
what are examples of viral eyelid infections
Herpes simplex palloric virus (warts around the lid margin) - may/may not cause red eye due to proximity to lid margin
30
a stye is an
infection of the root of the hair follicle - pulling out the lash releases the infection
31
herpes simplex needs to be treated with what
needs to be treated with an oral antiviral Redness on inside of eyelid - evert the eyelid- topical medicine needs to be given
32
when you see blisters on the tip of the noose in herpes zoster opthalmicus what should you do
When you see blisters on the tip of the nose - the surface of the eye must be examined because the nasocillary nerve supplies sensation to the surface of the eye (may be a corneal ulcer and they are unaware of it) (hutchinsons sign)- positive hutchinsons sign indicated reactivation of the varicella zoster virus on the trigeminal nerve , specifically in the ophthalmic branch
33
what would a sight threatning presentation of herpes zoster opthalmicus look like
Herpes zoster opthalmicus Sight threatening presentation = when surface of the cornea has turned white
34
why can malpoistion of the eyelids cause an red eye
Eyelashes are rubbing on the surface of the eye due to inwards turn of lid margin = inflammation Requires surgery
35
what can happen in llower lid margin has fallen away from the globe
Exposed fornicial conjuctiva , becomes red because of exposure , can happen in pts who have 7th nerve or facial nerve palsy Need to ensure pt can close eyelids , night time exposure will cause significant redness of the eyes, sx = required
36
subconjuctival haemhorrhage
not sight threatining uncomfortable/ foreign body sensattion if you cant see anything on posterior margin - may be a history of trauma benign condiiton can also be caused by coughing and sneezing
37
differentiation between discharge produced by viral infection and bacterial
viral infection watery discharge sticky/purlent = bacterial blood stained tears = severe vrial infection conditons such as diptheria can present with conjuctivits vision not affected may cuase blurring because of the discharge
38
viral infection vs allergic when eyelid inverted
viral infection = follicels allergic reaction = papillae
39
adenoviral infections
in cases of viral conjuctvitis white spots on the superfical layer of the cornea= sub epitheliel infiltrates- if affecting centre of the pupillary area then vision will be affected , however if in periphery then will get better - inflammatory response of the cornea to a viral infection if central cornea = affected then steroids should be given carefully
40
what are the three types of bacterial conjuctvitis caused by chlyamidia ,
depending on serotype can cause three types of infection and can cause trachoma = disease of poor hygiene adult inclusion conjuctivits = caused by an STI nenonatal conjuctivits - if mom is affected , passed through the birth caanl passage to the birth canal will cause the infants eyes to be affected
41
what is ABC treated with
chloremphenicol + fusidic
42
if an eyelid is white when inverted what could it be indicative of
white lid underenath the lid - when lid has been inverted - scarring because of repeat infection
43
trachoma is /....
causes infection by recurrent infection , potenitllay blinding condiion
44
what must you do if adult inlcusion conjuctivits happens
red eye+ discharge - so swab must be taken using a clean sterile cotton swab, rub against conjuctiva + send to lab for diagnosis
45
what is opthalmia neonatorium
Opthalmia neonatorium - conjunctivitis in the first 3 weeks of life
46
what is allergic conjuctvitis
Allergic conjuctitvits - acute type 1 (hypersensitivity) due to sudden exposure to allergen, Atopy = persons tendency to be reacting to allergens in an exaggerated manner , if someones has chronic itchy eyes all year ask for history of eczema + hay fever gives an indication that they are prone to having these conditions
47
giant papillary conjuctivits
Giant papillary conjunctivitis in people who wear CL = edge of cornea not fitting well, will continue to irritate , the conjuctiva lining the upper lid, that will cause inflammation and allergic reaction,
48
presentation of vernal keratoconjuctivits
Vernal keratoconjuctvitis , flip over the upper eyelid- very red + big papillae + discharge , papillae rub against eye when pt is blinking + may cause corneal ulcer These corneal papillae will therefore be treated with steroids
49
contact dermatitis and allergic conjuctvitis due to eye dropsn
Contact dermatitis and Allergic conjuctitvitis due to eye drops - causes redness of the eye around the skin , drops have seeped out the eye causing contact dermatitis
50
chemical conjuctivits
Chemical conjunctivitis - usually because of an injury with acid or an alkalia - urgency of wash out= more important , can take up to an hr of irrigation - wash out with water
51
if the whole eye is red and their are some red spots what is this indicative of
that is indicative of bleaching and that the blood supply is gone from that area - meaning that the whole of the corneal epithelium is gone - which is why you may get a diffuse green colour which is picked up as a epithelial defect (this is called limbal ischemia) because the blood supply is gone wheree their is a junction of cornea and sclera - depedning upon the extent of limbal isahemia if it is more than 180 degrees - serious sight threatening - can build up and cause increased intraocular pressure and intraocular inflammation.
52
are acid or alkalia injuries more worse
Alkali injuries are safer , when acid gets in touch with the surface of the eye causes couagulation of proteins , that prevents deeper penetration into the eye
53
what to do if presented with corneal foreign body
Corneal foreign body this can be taken out under topical anesthesisa oon a it amp , dont remove full foreign body , e.g. if iron rust becomes superficial over a period of time + can take out If left over a period over time in situ - attracts inflammatory blood vessels for it to heal and this can cause a scar , dosnt apear to be in the centre of the pupil so not sight threatening If you see corneal foreign body before sending patient way lift up top lid and look for what you call a sub tarsal foreign body To reveal this put a drop of fluroscein and you will see linear abrasions - everytime the person is blinking the foreign body is rubbing on the surface of the cornea so it can cause linear abrasions of things
54
dendritic ulcer presentation
Dendritic ulcer - branch like shape - reason being corneal nerves - looks like a branch of tree- this virus is a nuerotropic virus - spreads along the nerves - treatment topical antiviral= acyclovoir
55
herpes simplex keratitis shouldnt be treated with
- shouldnt be treated with steroid - enhances grow with steroid Geographical ulcer (amboeid ulcer) is caused - when has healed attracts blood vessles from the conjuctiva and will result in poor vision so is sight threatining
56
what stains will reveal what
Fluroscein staines any corneal defects Rose bengal will stain any diseased epithelium and will reveal an amboeid ulcer
57
what is the presentation of corneal infection: bacterial keratitis
Bacterial infections = commoner in people who wear soft contact lense (extended wear) or in trauma Commonest organism for corneal ulcer with contact lenses- acanthomeba (swimming with cl + sleeping with cl)
58
are corneal infections sight threatning
Corneal infections are serious they can cause sight loss - tretament is usually with intensified topical steroids + topical antibiotics
59
allergic corneal ulcer can produce what
marginal keratitis (inflammatory allergic reaction)
60
blepharitis can cause
Blepharitis - because the lid is opposed to the surface of the eye - causes secondary inflammatory response in the cornea - called marginal keratitis because if affects the margin of the cornea - because it is inflammation and not infection the treament is usually with steroids
61
acute anterior uveitis presentation
40% of people with iritis have systemic assocations e..g inflmmatiory bowel disease , psorasis important to ask history of any joint pain , mouth ulcers or bowel pain or skin changes with these conditions Also you can have patients with conditions such as tuberculosis and sarcodidis who first present with iririts so that is why it is important to investigate
62
how to differentiate between conjuctivitis and acute anterior uveitis
Unlike conjunctivitis which will be a painful condition / discomfort - this condition will not cause pain , usually one eye is affected unlike conjunctivitis and another feature is they will be extremely sensitive to light because of the inflammation of the iris Structure of uvea: iris , cillary body, choroid all one layer , if you have inflammation of the iris tissue what stops the cillary body being infglamed - caused a spasm , any light coming to the eye makes the spasm worse - also reduced va because the he pupil can become small and mishapen and because of anterior chamber activity
63
AAU clinical signs
clinical signs - white dots - keratiic percipitaes- inflammation is in the iris - cells in the ac - these cells form clumps in the corena and they stick to the bottom part of the cornea and they are called keratitic percipitates (keratiic= corena, precipitates = clump of cells) These are neutrophils and lymphocytes If you dont treat this then then the pupil will remain mishapen forever Posterior synachie= between the iris and the lens Anterior synachie = between the cornea and the iris Fibrin or intense inflammation causes the pouring out of protein from the iris blood vessels = fibrin - when you investigate send patients for routine test e..g. Sarcodoisis e.g. chest xray
64
another reason for red eye could be
Antoher reason for red eye could be that their is inflammation of the episclera and sclera Conjucitva covers sclera - most superficial part of sclera= episclera Difference between sclera and episclera = episclera = vascular has got a blood supply - episclear = thin vascular layer Usually presents in 30s and 40s and is benign - causes a bit of ache but no changes in the vision Scleritis = extremely rare usually presents with systemic inflammation= rheumatoid arthritis If paient has red eye and scleritis they will mention that the pain prevents them from going to sleep deep pain - can cause sclera to melt and the eye can lose its integrity - so it is a potentially sight threatening problem