Red blood cells Flashcards
What would you expect to happen to the following labs in the event of hereditary spherocytosis?
MCHC
RDW
unconjugated bilirubin
Increased MCHC
Increased RDW
Increased uncon bill
Heinz bodies and bite cells are associated with…
G6PDD
In this disease, HbF will be elevated and HbA will be absent
Beta thal major
This is characterized by Increased HbS, anisocytosis, and poikilocytosis
Sickle Cell
What are the Hb levels are after expected to be found in B thal minor?
Increased hbA2
HbF is increased
What disease are B tetramers of hemoglobin found in? What are these calleD?
HbH disease
hemoglobin Barts
Tetramers of gamma globulin are seen in….
hydros fetalis
In this disease, there is an issue with the GPI proteins, which cause lysis of the RBCs, specifically in a state where the body’s pH is lowered
Paraoxysmal nocturnal hemoglobinuria (PNH)
In this disorder, Schistocytes, Burr cells, Helmet cells, and triangle cells can be seen
Microangiopathtic hemolytic anemia
Autoantibodies to IF is seen in
Pernicious anemia
How can you differentiate a B12 deficiency from a folate?
Using the methymalonic acid levels: will be elevated in B12 and will stay normal in folate
homocysteine levels will increase in both
What are the expected effects on the following labs in iron deficiency anemia? HCT Hb Serum iron Serum ferritin TIBC serum hepcidin RDW
HCT decreased Hb decreased Serum iron decreased serum ferritin decreased TIBC increased serum hepcidin is decreased RDW is increased
In this disorder, inflammatory cytokines will be high
EPO levels will be low
serum ferritin will be high
TIBC will be low
anemia with chronic disease
This disorder is associated with a pancytopenia with bone marrow hypocellularity
Aplastic anemia
