Connective Tissue and Vas.

Question 1

What are the antibodies that will be seen in SLE?

Answer 1

dsDNA
Smith
ANA
C3, C4 will be decreased

Question 2

What would you expect the UA of an SLE patient to look like?

Answer 2

protein and casts

Question 3

How will the presence of lupus anticoagulant effect the aPTT

Answer 3

prolong it

Question 4

This disorder has + anti-histone Abs

Answer 4

Lupus like, drug induced

Question 5

What is a common clinical finding that is associated with neonatal lupus?

Answer 5

Complete heart block

Question 6

Renal crisis is characterized by 3 things which are…

Answer 6

Malignant HTN
Hemolytic anemia
Progressive renal insufficiency

Question 7

What antibody will be seen in Limited SCC

Answer 7

Anti-centromere

Question 8

Anti-Scl70 and Anti-RNA are seen in which disorder?

Answer 8

Diffuse SCC

Question 9

What is the major diagnostic test for sjogren syndrome?

Answer 9

Lip biopsy

Question 10

Which diagnostic factors will be present in Sjogren syndrome?

Answer 10

Polyclonal hyperglobinemia
Anti SSA
Anti SSB

Question 11

This disorder will have a +Anti-Jo1 and elevated CK and aldolase

Answer 11

Dermatomyositis

Question 12

This disorder will have a +Anti-Jo1 and an elevated CK

Answer 12

polymyositis

Question 13

This disorder will have Anti-cN1A autoantibodies and a mildly elevated CK

Answer 13

Inclusion body myositis

Question 14

Anti-basement membrane Abs will be seen in….

Answer 14

Goodpasture syndrome

Question 15

These disorders are ANCA positive

Answer 15

GPA (Wegeners)

Eopsinophilia Granulomatosis with polyangitis

Question 16

This disorder has a triad associated with it which is,
Recurrent mouth ulcers
Genital ulcers
Eye inflammation

Answer 16

Bechet syndrome

Question 17

______ is the presence of pustules at the site of sterile needle pricks

Answer 17

Pathergy; seen in Bechet

Question 18

HLA-B51 is seen in??

Answer 18

Bechet syndrome

Question 19

THE LUNGS ARE SPARED IN….

Answer 19

Polyarteritis nodosa

Question 20

This is also knowns as the pulseless disease

Answer 20

Takayasu disease

Question 21

This disorder will have an elevated ESR and CRP with clinical findings of a headache, jaw claudication, and visual abnormalities

Answer 21

Giant cell arteritis

Question 22

Which labs will be elevated in polymyalgia rheumatica?

Answer 22

Elevated ESR and CRP