Red Blood Cell Disorders

Question 1

Normal values of MCV ?

Answer 1

80-100

Question 2

4 types of microcytic anemias?

Answer 2

1) Iron deficiency anemia
2) anemia of chronic disease
3) sideroblastic anemia
4) thalassemia

Question 3

In which diseases, there is an increase risk for aplastic crisis with parvovirus B19 infection of erythroid precursors?

Answer 3

-Beta thalassemia major
-Hereditary spherocytosis
-sickle cell anemia

Question 4

In sideroblastic anemia, an iron overloaded state is seen. What is the most commonly seen congenital defect in the patients?

Answer 4

ALAS enzyme defect (rate limiting state in production of protoporhirin)