Rectal Cancer

Question 1

Treatment of locally advanced Rectal Ca

Answer 1

Remember that rectal cancer is REALLY hard to operate on
= when T3/4 = neoadjuvant chemoradiotherapy + surgery + adjuvant chemo

Question 2

Treatment of Rectal Cancer

Answer 2

In Stage II disease - long course chemoradiation prior to surgery.

Conventional fractionation chemoradiotherapy over 5.5 to 6 weeks using concurrent fluoropyrimidine-based chemotherapy is preferred over initial surgery if the patient can tolerate it.