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Oncology > Melanoma > Flashcards

Melanoma Flashcards

1
Q

Melanoma treatments

A
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2
Q

Adjuvant therapy in Melanoma

A

Is not currently standard of care in Australia, not PBSlisted

Combination BRAF + MEKi vs. Immunotherapy

Very active space

  • Inteferon is currently PBS approved in Australia for treatment of Stage III melanoma.
    • Low uptake due to poor OS benefit
    • High levels of toxicity

Current trial investigating:

  • Use of combination Ipilimumab/ Nivolumab vs. Nivolumab
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3
Q

Combination therapy (CTLA-4 + PD1 inhibitors) in met. melanoma

  • effect on survival
  • trade off
A
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4
Q

Temozolomide

A

Alkylating agent!

Metastatic melanoma

Myelosuppression!

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5
Q

Pembrolizumab and Nivolumab

A
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6
Q

Ipilimumab

A
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7
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Oncology (9 decks)

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