Reconstruction Flashcards

1
Q

Define the following:
Osteoconduction
Osteoinduction
Osteogenesis

A

Osteoconduction: Graft acts as a scaffold for vascular tissue and mesenchymal cells
Osteoinduction: Stimulation of osteoprogenitor cells to differentiate into new bone forming cells
Osteogenesis: Transfer of vital osteoblasts to contribute to the growth of new bone

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2
Q

Define allograft.

A

Graft from same species. Can provide osteoconduction and osteoinduction

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3
Q

Define autograft.

A

Graft from same individual. Provides osteoconduction, osteoinduction and osteogenesis

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4
Q

Define xenograft

A

Graft from non-human. Provides osteoconduction

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5
Q

Define alloplastic graft

A

Graft from a synthetic material

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6
Q

What is creeping substitution?

A

Process by which osteoclastic activity creates new vascular channels, with osteoblastic bone formation resulting in new haversian systems and osteogenesis from the graft

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7
Q

What are the contraindications to a tibial bone graft?

A

-History of surgery in area or hardware
-Acute infection over soft tissue

Relative: History of metabolic bone disease

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8
Q

How much bone can be harvested from a tibia?

A

-25 mL of cancellous bone

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9
Q

What is the surgical technique of a tibia bone graft?

A

-Knee partially flexed and medially rotated, prepped
-Inject local with epi
-2 cm incision directly over palpable ridge of Gerdy’s tubercle. Parallel to tibial plateau and oblique to long axis of tibia
-Layers: Skin, subcutaneous tissue, periosteum
-Small portion of anterior tibialis and fascia lata stripped to allow acces to the cortex
-Fissure burr to make a corticotomy
-Curette inserted and rotated to harvest cancellous bone
-Avoid risk of perforation at superior edge
-More fat in this bone, need to compact it
-Pack bovine microfibrillar collagen (platelet aggregator matrix) or gelatin sponge (blood clot matrix)
-Layered closure

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10
Q

What are complications associated with a tibia?

A

-Infection, gait disturbance, osteomyelitis, hematoma, seroma, fracture, violation of joint space.

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11
Q

How is ecchymosis/swelling of the lower leg/ankle treated post-op with tibia graft?

A

-Decreased by keeping limb elevated
-Normal weight-bearing permitted but avoid strenuous activity
-Resolves on own

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12
Q

How is a violation of the joint space or fracture of the tibia treated with a tibia graft?

A

-Non-weight bearing therapy
-Splinting
-Orthopedic surgery consult

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13
Q

How is post-op osteomyelitis treated s/p tibia graft?

A

-MRI to eval depth of invasion/true osteomyelitis
-Orthopedic surgery consult
-Infectious disease and wound therapy consult
-Possible hyperbaric oxygen, long term antibiotic therapy

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14
Q

How much bone can be obtained from an AICBG?

A

-50 cc (5 cm defect)

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15
Q

What is the harvest site of an AICBG?

A

-Anterior superior iliac spine and tubercle of ilium

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16
Q

What attaches to the ASIS?

A

-external oblique muscles
-tensor fascia lata

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17
Q

What is most common nerve encountered during AICBG?

A

-Lateral cutaneous branch of iliohypogastic nerve L1, L2

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18
Q

What is meralgia paresthetica and how is it caused?

A

-Dysesthesia and anesthesia of lateral thigh
-Damage to lateral femoral cutaneous nerve
-In 2.5% of patients this nerve comes within 1 cm of ASIS placing it at risk (usually most inferior nerve)

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19
Q

What is the blood supply for the AICBG?

A

-Deep circumflex iliac artery
-Most common bleeding is from superior gluteal artery

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20
Q

Describe the surgical technique for an anterior iliac crest bone graft.

A

-Retract skin medially
-4-6 cm incision placed 1-2 cm anterior to tubercle of ilium and 1 cm posterior to ASIS
-Infiltrate local w/ epi
-Incision is oblique along the cres
-Layers: Skin, subcutaneous tissue, scarpa’s fascia, muscular aponeurosis, periosteum
-Plan between TFL (laterally) and external oblique/transverse abdominus muscle (avascular plane)
-Medial approach (dissect iliacus)
-5 cm depth (cortical plate fuses), corticotomies
-Leave 3 cm bone to ASIS
-Bone wax or microfibrillar bovine collagen for hemostasis, may place drain
-Closure in layers

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21
Q

How is post-op hematoma managed with an AICBG?

A

-If non expanding, pressure packing may be applied
-If expanding, require surgical exploration

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22
Q

How is a massive hemorrhage managed during an AICBG?

A

-Likely from superior gluteal artery
-Caused by harvesting proximal to and or retracting too aggresively near the greater sciatic notch
-Tx: Exploration, ligation, embolization by IR
-Don’t blindly clip, can risk damage to sciatic nerve or superior gluteal nerve

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23
Q

How is post-op seroma managed s/p AICBG?

A

Needle aspiration vs pressure dressing

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24
Q

How is gait disturbance managed s/p AICBG?

A

-Usually self resolving. From excessive stripping of TFL
-Consult Physical therapy

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25
Q

How is a bony fracture managed from an AICBG?

A

-Caused by harvest too close to ASIS (stay at least 2 cm away)
-Pain management, bed rest
-Consult orthopedic surgery

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26
Q

How is an intra-abdominal injury managed from an AICBG?

A

-Surgical emergency, requires ex-lap

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27
Q

How is a post-op ileus managed from an AICBG?

A

-This is cessation of mechanical peristalsis of the bowel
-Tx: Bowel rest, electrolyte correction, NG tube for decompression, limit narcotics
-Consider pre-motility medicine like Reglan
-Usually self resolves, may obtain imaging to rule out bowel injury

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28
Q

How is sacroiliac instability managed s/p AICBG?

A

-Pain in lower back or pubis
-May need fusion if persistent pain

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29
Q

How is an abdominal wall hernia managed s/p AICBG?

A

-Risk factors: >4cm block harvest, female gender, obesity
-General surgery consultation

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30
Q

How much bone can be obtained from a posterior iliac crest?

A

100 cc (10 cm defect)

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31
Q

What is the blood supply to the posterior iliac crest?

A

-Subgluteal artery

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32
Q

Describe the surgical technique for a posterior iliac crest.

A

-Prone position, 210 degree reverse hip flexion
-6-10 curvilinear incision following course of posterior iliac crest
-Superior and inferior boundaries defined by superior L1-L3 and middle cluneal nerves S1-S3
-Incision ends (infeirorly), 3 cm lateral to gluteal crease
-Layers: Skin, subcutaneous, lumbodorsal fascia (seperates abdominal and gluteal musculature), and periosteum
-Gluteus maximus muscle stripped from tubercle
-5x5 cm osteotomy of lateral cortical plate
-Stay 4 cm from PSIS (avoid violation of sacroiliac joint)
-Hemostasis (avetene/bone wax)
-Layered closure, drain if needed

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33
Q

Where would bleeding be encountered during a posterior iliac crest graft, how is this managed?

A

-Superior gluteal artery
-Can cause post-op gluteal compartment syndrome
-Tx with ligation. may need ex lap or retroperitoneal approach
-May need IR embolization

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34
Q

How is a post-op urethral injury managed during a posterior iliac crest graft?

A

-Post-op hematuria, abdominal distention, ileus
-From excessive electrocautery near greater sciatic notch
-Urology consult indicated
-May need ureteral stent or surgical repair

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35
Q

What nerve injury can occur from a posterior iliac crest graft and how does it present?

A

-Cluneal nerves (posterior pelvic pain radiating to buttocks)

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36
Q

What type of graft is an anterolateral thigh flap, what is the artery/vein supply, how large of a graft/pedicle can be obtained?

A

-Fasciocutaneous (skin, muscle, fascia)
-Descending branch of lateral circumflex femoral artery
-5-7 cm pedicle (1.5-3 mm diameter vessel), very large flap 10-25 cm

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37
Q

Describe the surgical technique of an ALT flap.

A

-Draw line from anterior-superior iliac crest to lateral aspect of patella
-Draw a 5 cm circle at midpoint of line (likely where perforators can be identified)
-Center flap over perforators
-Make skin incision along medial margin of flap (skin, subcutaneous tissue, fascia over rectus femoris muscle)
-In subfascial plane, carry laterally until perforating vessels are identified
-Dissect the septum between the vastus lateralis and rectus femoris muscles to identify the pedicle
-Trace back pedicle to the lateral circumflex femoral artery. Incise flap around the lateral aspect
-Completely dissect the fasciocutaneous portion
-When ready, back cut on flap to desired size
-Vessels are clamped proximally and ligated
-Deliver flap to donor site
-Can usually close primarily, may require skin graft

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38
Q

How is muscle herniation managed s/p ALT flap?

A

-From vastus lateral and rectus femoris
-Requires exploration and repair. May require mesh

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39
Q

How is rectus femoris muscle necrosis managed s/p ALT flap?

A

-Uncommon
-From ligation of lateral circumflex artery proximal to take-off of the descending branch
-Preventative management: Place vessel loop at planned harvest spot and evaluate prior to definitive ligation

40
Q

How is compartment syndrome managed s/p ALT flap?

A

-Release of deep fascia
-Debridement with VAC therapy

41
Q

What type of flap, pedicle length/caliber, and vasculature is a radial forearm free flap?

A

-Fasciocutaneous flap
-Radial artery, venae comitantes or cephalic vein
-Long pedicle, 2-4 cm caliber

42
Q

What are pre-op considerations for a radial forearm free flap?

A

-Allen test to determine acceptable ulnar collateralization

43
Q

Describe the radial forearm harvest technique.

A

-Radial artery palpated and marked
-Flap drawn on skin. Distal aspect 1 cm from wrist crease
-Tourniquet utilized and inflated to 250 mmHg5

44
Q

How is post-op tendon exposure, necrotic tissue treated s/p radial forearm harvest?

A

-Debride tissue, attempt second skin graft
-Allow to heal secondarily depending on size

45
Q

How is post-op hand ischemia treated s/p radial forearm harvest?

A

-Normally avoided with Allen test or color flow doppler
-Can occur if radial artery is major blood supply of the hand, damage to ulnar artery, insufficient collateral blood flow
-Treat with interpositional vein graft to the divided stump from either the saphenous or cephalic vein

46
Q

What is the typical size of a bone graft obtained from a fibular free flap.

A

Bony height: 9-15 mm
Length: 25 cm

47
Q

What is the vascular supply of the fibula free flap?

A

Peroneal artery
Venous comitantes

48
Q

What is the caliber and length of the pedicle for a fibula free flap?

A

1.5-2.5 mm caliber
2-6 cm length

49
Q

How are the fasical components of the fibula classified?

A

-Anterior and posterior (separated by tibia and fibula with their interosseous septum)
-Anterior has an anterior and lateral subdivision (separated by the anterior intermuscular septum)
-Posterior divided into deep and superficial components by the transverse intermuscular septum
-Lateral and posterior are separated by the posterior intermuscular septum

50
Q

What fascial plane/septum is the skin perforators located (for a skin paddle harvest)?

A

Posterior intermuscular septum

51
Q

What medical co-morbidities would affect a fibular free flap harvest?

A

-CAD
-Peripheral vascular disease
-Smoking
-History of claudication
-History of edema
-History of venous thrombosis
-Prior trauma

52
Q

What arteries should you palpate on pre-op exam for a fibula free flap harvest?

A

Palpate dorsalis pedis and posterior tibial pulses

-Modified allen test (apply pressure to dorsalis pedis artery and palpate for posterior tibial pulse and vice versa)

53
Q

What imaging is relevant with a fibular free flap harvest?

A

-Magnetic resonance angiography
-Computed tomographic angiography
-Conventional angiogram
-Color flow dopler imaging

54
Q

What are findings in arterial supply that would affect FFF?

A

-Kim-Lippert Classification:
-Type III: Hypoplastic/aplastic branching of infra-popliteal artery (10%). 3 subgroups either 2 vessel runoff or single vessel peronia arteria magna)
-Type IV: Hypoplastic (relative), aplastic (absolute): Perioneal artery caliber

55
Q

Describe the fibular free flap technique.

A

-Tourniquet inflated 250-350 mmHg
-Place a long anterior curvilinear incision to transverse intermuscular septum, along anticipated skin paddle.
-Incise skin and soft tissue to the fascia overlying the peroneus muscle
-Identify intermuscular septum and located perforators to the skin (typically located in middle and distal thirds of fibula)
-Dissect along the length of the anterior aspect of the fibula (peroneus longus, peroneus brevis, extensor hallucius longus)
-Continue dissection along the bone to the medial aspect (interosseous membrane)
-Proximal and distal fibula bone cuts (save 6-8 cm on both ends to maintain ankle and knee stability)
-Make posterior skin buts down to subfascial plane
-Retract fibula laterally, transect interosseous membrane to separate fibula from tibia
-Distal peroneal artery and veins are identified. Ligate and transect distal pedicle
-Disect pedicle from distal to proximal
-Preserve cuff of muscle along fibula (saves nutrient branches to fibula bone)
-Transect hallucis longus and ligate pedicle proximally (more proximally, the longer and greater diameter the pedicle)
-Flap harvested and prepared
-Insertion and anastomosis
-Re-approximate lateral compartment, close in layered fashion in tension free. Skin graft likely required

56
Q

Where is the best location to obtain a calvarial bone graft?

A

-Parietal area.
-2 cm away from midline and 2 cm away from squamous portion of temporal bone

-Accessed via coronal incision

57
Q

Describe how the vessels exit and where the skin paddle is for a right and left mandibular defect?

A

Right mandibular defect: If obtaining a right fibula, vessels come out anteriorly if skin covers mucosal defect and posteriorly if skin paddle covers neck/external defect
Left fibular: Vessels come out anteriorly for external defect or posteriorly for mucosal coverage

Think hand on fibula. Fingers represent vessels and palm is the pedicle.

58
Q

What are common recipient vessels for oral cavity and lower facial reconstruction?

A

-Facial artery/veing
-External jugular vein

59
Q

What arteries are used if the facial artery is not sufficient as a recipient vessel?

A

-Lingual or superior thyroid artery
-Transverse cervical artery

60
Q

What veins can be used if the external jugular cannot be used as a recipient?

A

-Internal jugular

-Should avoid anterior jugular (due to tracheostomy)

61
Q

How are vessels handled during a neck dissection to best preserve if needed for reconstruction?

A

-Gently tied with silk ties or vascular clips and dissected sharply

-Avoid electrocautery
-Avoid excessive handling

62
Q

What is the most common type of anastomosis?

A

-End to end

63
Q

What are techniques to overcome vessel discrepancy?

A

-Trimming smaller vessel back
-Dilating smaller vessel gently
-Spatulation (Cut longitudinally of smaller vessel and suture to end of anastamosis)
-Bevel edge of smaller vessel up to 30 degrees
-End to side anastomosis

64
Q

What type of suture is used for anastomoses?

A

-9/0 nylon with tapered point needle

65
Q

How are veins vs arteries anastomosed microvascular surgery?

A

-Arteries: Hand sutured
-Veins: Venous couplers (best when vessels are same size

66
Q

What is the most common causes of vascular failure of a flap?

A

-Venous congestion (4x more likely). Most likely occurs in first 48h
-Arterial thrombosis

67
Q

How does aspirin work and how long should a patient be on it s/p microvascular surgery?

A

-Blocks thromboxane A2 production (blocks vasoconstrictor activity) and aids in platelet binding
-Usually started post-op and on for 30-90 days

68
Q

How does heparin work and how is it used in microvascular surgery?

A

-Binds to antithrombin III. Prevents activation of factors 2, 12, 9, 10.
-Not used much due to risk of bleeding and hematoma formation
-Heparin irrigation utilized as a vessel irrigant. Helps with antithrombotic effects in vessel walls

69
Q

How does dextran work and how is it used in microvascular surgery?

A

-Electrochemical and rheological effect on vessel wall and red blood cells
-Improve vascular patency

-Must test for antigenicity (or can cause pulmonary edema, respiratory distress, renal damage, cardiac overload)

70
Q

What are the common causes of flap issues and how is it treated?

A

-Structural: Pedicle/perforator twisted, stretched or kinked, hematoma causing compression
-Treat by taking back to OR and exploring the flap

71
Q

How is a pinprick test done?

A

-Medium gauge needle used to pierce flap

-Arterial occlusion will have minimal to no bleeding. Decreased turgor of tissue
-Venous occlusion will cause rapid bleed of dark blood. Increased tissue turgor

72
Q

How is a tracheostomy preformed?

A

-Identify the thyroid notch, cricoid cartilage, SCM muscles, and sternal notch
-Half-way between sternal notch and cricoid cartilage, a transverse incision is marked (SCM Lateral most point)
-Local anesthetic to incisino
-Incision through skin, into subcutaneous tissue
-Blunt dissection until superficial layer of deep cervical fascia seen. Vertical incision through this to avoid damage to anterior jugular veins
-Strap muscles are next. The median raphe between the infrahyoid strap muscles are divided and retracted. Laterall retract sternohyoid and sternothyroid muscles
-Thyroid isthmus retracted superiorly
-Treachea visualized, divide pretracheal fascia
-Anesthesia deflates ETT
-Transverse incision made through membranous trachea between 2nd and 3rd rings. (T incision or Bjork flap)
-Anesthesia slowly removes ETT just superior to trach site
-Lubricated trach tube inserted
-Confirm end-tidal CO2
-Secure trach, remove previous ETT

73
Q

Where is most common post-op bleeding from a trach, how is it managed?

A

-Usually from anterior jugular vein or inadequate control of vascular thyroid
-Avoid electrocautery intra-op due to recurrent laryngeal nerve
-Use bipolar cautery
-Use Surgicel if post-op bleeding

74
Q

How is a tracheoesophageal fistula managed?

A

-Muscle flap to repair esophagus with prolonged bypass of esophagus with NG tube

75
Q

What is the blood supply to a pectoralis major flap?

A

-Pectoral branch of thoracoacromial artery, lateral thoracic artery, superior thoracic artery and intercostal artery
-Venae comitantes of accompanying arteries, drain to axillary vein

76
Q

What is the blood supply to the temporoparietal fascia flap?

A

-Superficial temporal artery and vein
-Auriculotemporal nerve

77
Q

How is the facial nerve mapped with a temporoparietal fascia flap?

A

-Runds deep to the temporal fascia
-Line drawn from the tragus to a line 3 cm above and 2 cm lateral to the supraorbital rim surgically
-Frontal branch is 1.5 cm lateral and superior to the eyebrow

78
Q

How is a temporoparietal fascia flap harvested?

A

-Doppler Superficial temporal artery
-Incision marked through preauricular crease in front of tragus. Extends superficially inta a hemicoronal incision
-Dissection through subcutaneous fat
-Release fascia with the desired pedicle from the underlying temporalis muscle
-Separate galea from temporoparietal fascia
-Release is completed in subgaleal areolar tissue (Merkel’s space) down to zygomatic arch
-Subcutaneous tunnel should be formed to allow extension of flap to defect

79
Q

How is alopecia avoided during temporoparietal fascia harvest?

A

-Deeper dissection deep to hair follicles

80
Q

How is temporal hollowing treated s/p temporoparietal fasica harvest?

A

-Can volumize bone with hydroxyapatite. Fat grafting, custom implants

81
Q

What are the components of the buccal fat pad, what is the blood supply?

A

-3 lobes: Anterior, intermediate and posterior
-Posterior has four extensions: Buccal, pterygoid, pterygopalatine, temporal

-Buccal artery, deep temporal branch of maxillary artery, superficial temporal artery

82
Q

What is the limit of upper lip primary closure? What are techniques of primary closure?

A

-Defects up to 1/4 upper lip

-V incision

83
Q

What is the limit of lower lip primary closure? What are the techniques?

A

-Defects up to 1/3 lower lip

-V or wedge resection

84
Q

Describe an Abbe flap?

A

-For upper lip 1/3-2/3.
-Based on inferior labial artery
-Triangular wedge from lower lip is designed.
-Flap raised and transposed 180 degress and inset. Donor site closed directly
-Division occurs 21 days later

85
Q

Describe a Karapandzic flap.

A

-Rotational advancement flap
-Remove lesion in rectangular full thickness fashion
-Semicircular partial thickness incisions in skin and mucosa are performed from the edge of the skind efect towards the nasolabial and labiomental folds bilaterally
-Vascular and nerves are identified and released to allow strech
-Incisions are not full thickness so facial nerves and branches are preserved

86
Q

Describe an estlander Flap.

A

-For pericommissural defects
-Apex of flap made into the nasolabial or labiomental crease
-Flap transposed 180 degrees
-Results in smaller oral stoma and indistinct commisure which may require more surgery

87
Q

Describe the classification for maxillary defects.

A

Brown Classification
Vertical:
-Class I: Defect of the mid-face or maxillary alveolus
-Class II: Defect includes oral-antral communication
-Class III: Includes inferior orbital rim
-Class IV: Includes exenteration of orbital contents
-Class V: Orbitomaxillary defects
-Class VI: Nasomaxillary defects

Horizontal:
-Class A: Central palatal defect
-Class B: 1/2 or less of unilateral palate/alveolous
-Class C: Anterior maxillary defect
-Class D: Greater than 1/2 palatal or alveolar defect

88
Q

Which fibula laterality is best for maxillary defect?

A

-Contralateral fibula
-Skin paddle will be towards oral cavity
-Pedicle coming off posterior of flap (best for tunneling to neck for anastomosis)

89
Q

How much bone can you obtain from a fibula?

A

-About 25-35 cm (depending on height of patient)
-Bone height varies from 9-15 mm

90
Q

What is a normal three vessel runoff?

A

-Show the popliteal artery branches into the anterior tibial artery, posterior tibial artery and peroneal artery
-Commonly the peroneal artery branches from the posterior tibial artery

91
Q

What is a double barrel fibular flap?

A

-Involves removal of a 1 cm segment of the fibular bony segment and the bone flap is folded upon itself to increase the height or reconstruction

92
Q

What is an equinovarus deformity and how is it prevented? What nerve controls sensation to the atnerior and lateral calf and dorsum of the foot?

A

-Equinovarus deformity: Club food
-Injury to common peroneal nerve
-Iatrogenic dissection or excessive traction (Wraps posterolaterally around neck of fibula
-Leave 6-7 cm segment of bone attached to the knee, identify nerve early

93
Q

How do you manage a positive margin with an ameloblastoma when re-constructed with a fibula?

A

-Requires re-resection
-Allow 6 weeks of healing (pedicle should have enough healing)
-Careful dissection
-Can graft gap with non-vascularized graft

94
Q

What do you do if SCCa had a positive margin?

A

-Re-excision when feasible
-Adjuvant chemotherapy and radiation are recommended

95
Q

What are the contraindications to a fibula free flap?-

A

-Peronea arteria magna (one dominant peroneal artery perfuses whole foot
-Two vessel runoff
-Open wound of the leg

96
Q

What is the difference between hypoglobus and orbital dystopia?

A

-Hypoglobus is the inferior displacement of the globe due to lack of bony orbital support. Usually seen in trauma and midface reconstruction

-Orbital dystopia is the displacement of the entire orbit. Commonly seen in craniofacial patients. Can see horizontal hypertelorism or vertical discrepancy

97
Q

What is the difference of hypernasality and hyponasality?

A

-Hypernasality: Airflow escapes into the nasal cavity. Often from velopharyngeal dysfunction, associated with multiple syndromes

-Hyponasality: Air passage into the nasal cavity is restricted as seen with enlarged tonsils, inflammation and swelling from any number of etiologies (common cold, deviated septum, tumors)