Recombinant Cytokines and Their Clinical Uses Flashcards

1
Q

What is the clinical use of this recombinant cytokine?

Aldesleukin (IL-2)

A

Renal cell carcinoma;

Metastatic melanoma

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2
Q
What is the clinical use of this recombinant cytokine?
Epoetin alpha (erythropoetin)
A

Anemias (esp in renal failure)

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3
Q

What is the clinical use of this recombinant cytokine?

Filgrastin (G-CSF)

A

Recovery of bone marrow

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4
Q

What is the clinical use of this recombinant cytokine?

Sargramostim (GM-CSF)

A

Recovery of bone marrow

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5
Q

What is the clinical use of this recombinant cytokine?

IFN-alpha

A

Chronic hepatits B and C;
Kaposi sarcoma;
Malignant melanoma

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6
Q

What is the clinical use of this recombinant cytokine?

IFN-beta

A

Multiple sclerosis

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7
Q

What is the clinical use of this recombinant cytokine?

IFN-gamma

A

Chronic granulomatous disease

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8
Q

What is the clinical use of this recombinant cytokine?

Romiplostim, eltromopag (thrombopoietin receptor agonists)

A

Thrombocytopenia

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9
Q

What is the clinical use of this recombinant cytokine?

Oprelvekin (IL-11)

A

Thrombocytopenia

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