Recombinant Cytokines And Clinical Use

Question 1

Bone marrow stimulation

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Answer 1

1)Erythropoietin;Epoetin alfa: anemias  
   (especially in renal failure)
2)Colony stimulating factors:leukopenia;
    Filgrastim, Sargramostim:leukopenia
3)Thrombopoietin;Romiplostim:autoimmune 
    thrombocytopenia

Question 2

Immunotherapy

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Answer 2

1)interleukin-2; Aldesleukin: renal cell
   carcinoma, metastasis melanoma
2)interferon;
    IFN-alpha:chronic hepatitis C,B
    IFN-beta:multiple sclerosis
    IFN-gramma:chronic granulomatous dz.