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055. My HDM Test 1 > Recognition of microbial products through TLRs > Flashcards

Recognition of microbial products through TLRs Flashcards

1
Q

TLR1:TLR2 heterodimer (Provide: Ligands, Cells carrying receptor, and Location of receptor)

A

Ligands: Lipopeptides/GPI
Cells Carrying Receptor: Monocytes, DCs, Eosinophils, basophils and mast cells
Location: Plasma membrane

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2
Q

TLR2: TLR6 heterodimer

A

Ligands: Lipoteichoic Acid/Zymosan

Cells Carrying Receptor: Monocytes, DCs, eosinophils, basophils, mast cells

Location: Plasma membrane

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3
Q

TLR 3

A

Ligands: Double stranded viral RNA

Cells Carrying Receptor: NK cells

Location: Endosomes

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4
Q

TLR4:TLR4 homodimer

A

Ligands: lipopolysacchride

Cells Carrying Receptor: Macrophages, DCs, mast cells, eosinophils

Location: Plasma membrane

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5
Q

TLR5

A

Ligands: flagellin

Cells Carrying Receptor: intestinal epithelium

Location: plasma membranes

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6
Q

TLR7

A

Ligands: Single-stranded viral RNAs

Cells Carrying Receptor: Plasmacytoid dendreitic cells, NK cells, eosinophils, B cells

Location: Endosomes

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7
Q

TLR8

A

Ligands: Single stranded viral RNA

Cells Carrying Receptor: NK cells

Location: Endosomes

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8
Q

TLR9

A

Ligands: Unmethylated CpG-rich DNA

Cells Carrying Receptor: Plasmcytoid dendritic cells, B cells, eosinophils, basophils

Location: Endsomes

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9
Q

TLR10 homodimer and heterodimers with TLR 1/2

A

Ligands: Unknown

Cells Carrying Receptor: Plasmcytoid dendritic cells, B cells, eosinophils, basophils

Location: Unknown

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10
Q

bacteria

A

TLR 1 2 4 5 9

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11
Q

viruses

A

TLR 3 7 8 9

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12
Q

fungi

A

TLR 2 6

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055. My HDM Test 1 (10 decks)

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