recitation 9 Flashcards
wild type alleles
most prevalent version of a gene in a wild population
polymorphism
> 1 common allele considered to be wild-type
mutant allele
less common version of a gene
recessive
protein is not as effective - less functional protein - most random mutations
dominant
effect phenotype with one copy
3 types of dominant
- gain of function
- dominant-negative
- haplo-insufficiency
incomplete penetrance
when they old the dominant gene but it does not express in the phenotype, not penetrating the population
incomplete dominance
phenotype of heterozygote is intermediate of homozygous dominant and recessive individuals
ex. pink flower
co-dominance
multiple alleles are expressed in a heterozygote, each allele encodes a functional protein but they are different in sequence
ex. abo blood type
overdominance
heterozygote more vigorous than the two homozygous
types of over dominance
- disease resistance
- homodiner formation
- variation in functional activity
sex-influenced alleles
dominant in one sex/ recessive in other
sex limited alleles
expressed in only one sex
lethal alleles
mutations from efficient genes, result in lethality and can be conditional
pleiotropy
single gene has multiple effects on the phenotype of an organism