recitation 10 Flashcards
crossing over
recombination between homologous chromosomes during meiosis
recombination
distance between 2 loci determines how likely they are to undergo recombination
genetic mapping
determine order + estimate distance between linked genes
map distance
of recombinant offspring / total # of offspring
how to create a linkage map
test cross = how often we get recombinant offspring we can determine distance between 2 loci
test cross
F1 heterozygous (AaBb) x Homozygous recessive individual (aabb)
recombination frequency
(recombinants / total offspring) x 100%
Chi Sqaure Analysis
null hypothesis - no relationship
alternative hypothesis - there is a relationship
Chromosome structure changes
deletion, duplication, inversion, translocation
deletion
region of chromosome lost
duplication
portion of chromosome is repeated
Inversion
rearrange gene sequence to the opposite orientation
translocation
segment of a chromosome becomes attached to a non-homologus chromosomes - alter the location of a segment of a chromosome
Changes in chromosome #
Aneuploidy
Aneuploidy
variation in # of single chromosome within a set