Receptors and signalling

Question 1

what does a receptor do?

Answer 1

transmission of a message from outside of a cell to its internal effects

Question 2

Ion channels

Answer 2

binding opens/closes channel to diffusive flow
can be voltage gated or ligand gated
eg neurotransmitters

Question 3

G Protein Coupled Receptors

Answer 3

Binding activates G proteins which start phosphorylation chains. G proteins are membrane proteins

Question 4

Kinase receptors

Answer 4

starts phosphorylation chains directly binding on outside results in activation on inside

Question 5

Antagonist action

Answer 5

binds but turns off signalling capacity –> blocks against binding and stops changing to natural state

Question 6

Agonist action

Answer 6

binds to provoke a signal from a receptor via a confrontational change.