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Biochemistry > Distribution > Flashcards

Distribution Flashcards

1
Q

Distribution

A

reversible transfer of drug to and from systemic circulation

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2
Q

factors affecting distribution

A
  • Pka
  • lipophilicity
    -plasma protein binding (PPB)
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3
Q

bioavailability

A

only unbound compounds are available for distribution

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4
Q

serum albumin

A

acidic preference

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5
Q

alpha - 1 - acid glycoprotein

A

basic preference

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Biochemistry (22 decks)

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