Metabolism Flashcards

1
Q

Metabolism

A

a chemical alteration of a drug by the living system to enhance water solubility and excretion

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2
Q

Factors affecting metabolism

A

Structure of drug
structure complexity (sites for metabolism)
blocked altered site for metabolism

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3
Q

Phase 1

A

Functional group changes, make sites for conjugation

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4
Q

Phase 2

A

Conjugation to hydrophilic units

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