Metabolism Flashcards
1
Q
Metabolism
A
a chemical alteration of a drug by the living system to enhance water solubility and excretion
2
Q
Factors affecting metabolism
A
Structure of drug
structure complexity (sites for metabolism)
blocked altered site for metabolism
3
Q
Phase 1
A
Functional group changes, make sites for conjugation
4
Q
Phase 2
A
Conjugation to hydrophilic units