Reactive Leukocyte Disorders Flashcards
1
Q
-defective leukocyte adhesion b/c of mutations in beta chain of CD11/18 integrins
A
leukocyte adhesion deficiency
2
Q
-mutation in fucosyl transferase required for synthesis of sialylated oligosaccharide (receptor for selectins)
A
leukocyte adhesion deficiency
3
Q
defective oxidative burst
A
chronic granulomatous disease
4
Q
defective membrane component, defective oxidative burst
A
X linked CGD (X-men)
5
Q
defective cytoplasmic component, defective oxidative burst
A
AR CGD
6
Q
decreased MPO-H202 systmem
A
MPO deficiency
7
Q
decreased leukocyte function b/c of mutations affecting lysosomal membrane traffic
A
Chediak-Higashi